Vitamin D: Relief From Diarrhea

Takeaways:

Vitamin D supports gut health and immune function

Low vitamin D levels may increase diarrhea risk

Supplementation could help manage certain types of diarrhea

Proper dosage and monitoring are important for safety

Sunlight exposure aids natural vitamin D production

Vitamin D works well with other diarrhea treatments

Understanding Vitamin D

Vitamin D is a vital, fat-soluble nutrient for human health.[1] It primarily exists as vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).[2] These compounds are crucial for absorbing calcium, maintaining strong bones, and supporting a healthy immune system.[3]

Our bodies can naturally produce vitamin D when our skin is exposed to sunlight.[4] We also get vitamin D through the food we eat and through supplements.[5] Foods like fatty fish, egg yolks, and fortified milk products are good sources of vitamin D.[6]

Recent studies show that vitamin D plays a role in our gut health.[7] It helps maintain the intestinal barrier and regulates the balance of bacteria in our gut (the gut microbiome).[8] These functions may explain why it is connected to managing diarrhea.[9]

The Vitamin D-Diarrhea Connection

How Vitamin D Impacts Gut Function

Vitamin D helps keep the intestinal barrier strong.[10] This barrier prevents harmful substances from entering the bloodstream. A strong barrier can help reduce inflammation and lower the chance of experiencing diarrhea.[11]

Vitamin D also influences the gut microbiome, which is the community of microorganisms in our digestive system.[12] A balanced microbiome is essential for good digestion and a healthy immune system.[13] Vitamin D helps maintain this balance, potentially decreasing the likelihood of diarrhea.[14]

Here are some ways vitamin D impacts gut health:

Strengthens intestinal barrier
Regulates gut microbiome composition
Reduces inflammation in the digestive tract
Enhances nutrient absorption

Vitamin D Deficiency and Diarrhea

Low levels of vitamin D have been linked to a higher risk of diarrhea.[15] This connection is particularly noticeable in children, older adults, and people who don’t get much sun exposure, as they are more prone to vitamin D deficiency.[16]

A lack of vitamin D can weaken the gut’s protective barriers.[17] This may make you more likely to get infections and experience inflammation, both of which can lead to diarrhea.[18]

Cause of Vitamin D Deficiency	Potential Impact on Gut Health
Limited sun exposure	Weakened intestinal barrier
Poor dietary intake	Imbalanced gut microbiome
Malabsorption disorders	Increased inflammation
Certain medications	Reduced immune function

Vitamin D’s Role in Immune Function

Vitamin D helps regulate the immune system.[19] It impacts both the initial and longer-term immune responses.[20] This nutrient helps activate immune cells and controls their actions.[21]

In the gut, vitamin D reduces inflammation by suppressing molecules that cause inflammation.[22] It also increases the production of molecules that reduce inflammation.[23] This balance is important for maintaining gut health and preventing diarrhea.[24]

Here are some steps on how vitamin D helps the immune system fight diarrhea-causing pathogens:

Activates immune cells in gut-associated lymphoid tissue
Enhances production of antimicrobial peptides
Regulates T-cell function to balance immune response
Reduces excessive inflammation in the intestinal lining
Supports the integrity of the gut barrier

Research on Vitamin D and Diarrhea

Clinical Studies

Several studies have explored the link between vitamin D and diarrhea. One study in children found that vitamin D supplements reduced how long acute diarrhea lasted.[25] Another study in adults with inflammatory bowel disease showed their symptoms improved with vitamin D treatment.[26]

Research has also looked at specific groups of people. Older adults with low vitamin D levels experienced more frequent diarrhea.[27] Supplementing their diet with vitamin D reduced how often they had diarrhea and how severe it was.[28]

Mechanisms of Action

Vitamin D may help reduce diarrhea symptoms in a few ways. It helps strengthen the intestinal barrier, which reduces fluid loss.[29] It also regulates the gut microbiome, promoting the growth of beneficial bacteria.[30]

Vitamin D may also help prevent certain types of diarrhea. Its effects on the immune system may help the body fight off infectious diarrhea.[31] It could also reduce inflammation in conditions like inflammatory bowel disease.

Here are some ways that vitamin D is thought to help with diarrhea:

Strengthens tight junctions between intestinal cells
Enhances antimicrobial peptide production
Modulates gut microbiome composition
Reduces intestinal inflammation
Improves calcium absorption in the gut

Vitamin D Supplementation for Diarrhea

Dosage Considerations

The recommended daily amount of vitamin D varies depending on your age and health. Most adults need about 600-800 IU per day.[32] However, higher doses may be needed to help relieve diarrhea.[33]

Several factors influence the ideal vitamin D dosage, including your current vitamin D levels, how severe your symptoms are, and your general health. Your weight, skin color, and how much sun you get also play a role in your vitamin D needs.

Age Group	Recommended Daily Intake	Potential Therapeutic Dose for Diarrhea
Infants	400-1000 IU	1000-2000 IU (under medical supervision)
Children	600-1000 IU	1000-4000 IU
Adults	600-2000 IU	2000-5000 IU
Elderly	800-2000 IU	2000-6000 IU

Forms of Vitamin D Supplements

Vitamin D supplements come in different forms. The most common are D2 (ergocalciferol) and D3 (cholecalciferol).[34] D3 is often preferred because it is more effective at raising the level of vitamin D in your blood.[35]

Different forms of supplements are absorbed at different rates. Liquid drops may be absorbed faster than tablets.[36] Soft gels that contain oil can help with the absorption of this fat-soluble vitamin.[37]

Here are some pros and cons of different types of vitamin D supplements:

Tablets: Convenient, but may have slower absorption
Liquid drops: Fast absorption, easy dose adjustment
Soft gels: Good absorption, may be easier to swallow
Chewables: Tasty option for children, but may contain sugar
Sprays: Quick absorption, but may be more expensive

Dietary Sources of Vitamin D

While supplements are often used, getting vitamin D from food is also beneficial. Natural sources include fatty fish, egg yolks, and mushrooms that have been exposed to UV light.[38] These foods provide vitamin D along with other important nutrients.

Fortified foods also provide vitamin D. Many dairy products, plant-based milk alternatives, and cereals have vitamin D added to them. These options can help you increase your vitamin D intake, especially if you don’t get much sun.

Here are some top vitamin D-rich foods that can benefit your gut health:

Salmon
Sardines
Cod liver oil
Egg yolks
UV-exposed mushrooms
Fortified milk (dairy or plant-based)
Fortified orange juice
Fortified yogurt

Sunlight Exposure and Vitamin D Production

Our skin produces vitamin D when exposed to sunlight.[39] UVB rays trigger the production of vitamin D3 from a form of cholesterol in our skin.[40] This process is a significant source of vitamin D for many people.

Several factors can affect how much vitamin D our skin produces from sunlight. These factors include your skin color, the time of day, the season, and where you live. Using sunscreen, while important for skin health, can also reduce vitamin D production.[41]

Here are some steps you can take to safely maximize your vitamin D production through sunlight:

Expose arms and legs to sunlight for 10-30 minutes
Aim for midday sun exposure when UVB rays are strongest
Consider shorter exposure times for fair-skinned individuals
Increase exposure time gradually to avoid sunburn
Be aware that glass blocks UVB rays
Balance sun exposure with skin cancer prevention measures

Potential Risks and Side Effects

While vitamin D is essential, too much of it can lead to negative effects. Vitamin D toxicity, although rare, can occur if you take very high doses over time.[42] It’s more common with supplements than from sun exposure or diet.

Symptoms of vitamin D toxicity can include nausea, vomiting, and weakness.[43] In severe cases, it can lead to kidney problems and irregular heart rhythms. Regular monitoring can help prevent these issues.

Here are some signs of a vitamin D overdose to watch for:

Nausea and vomiting
Loss of appetite
Excessive thirst
Frequent urination
Confusion
Weakness
Kidney stones
Irregular heartbeat

Combining Vitamin D with Other Treatments

Vitamin D can be used alongside other treatments for diarrhea.[44] It may help make probiotics and oral rehydration solutions work better. Its immune-boosting properties could also support antibiotic treatments for infectious diarrhea.

Vitamin D may work together with other nutrients. Calcium and vitamin K2 work closely with vitamin D in the body.[45] Magnesium is also important for how your body uses vitamin D.[46]

Treatment	Effect Alone	Effect with Vitamin D
Probiotics	Restores gut flora	May enhance probiotic survival
Antibiotics	Kills harmful bacteria	Could boost immune response
Oral rehydration	Replaces fluids and electrolytes	May improve electrolyte absorption
Antidiarrheal medications	Reduces bowel movements	Could address underlying causes

Special Considerations for Different Groups

Children and Infants

Children have unique vitamin D needs for growth and development. Getting enough vitamin D is crucial for bone health and immune function.[47] If a child has diarrhea, vitamin D may help reduce how long it lasts and how severe it is.

When giving supplements to young children, it’s important to use careful dosing. Liquid drops are often the preferred method for infants. Parents should talk to a doctor to determine the right dosage for their child based on their age and health.

Elderly

Older adults are at a higher risk of vitamin D deficiency.[48] This is because their skin produces less vitamin D, they may get less sun exposure, and they may not get enough vitamin D from their diet. This deficiency can contribute to various health issues, including digestive problems.

Vitamin D supplements can help older adults prevent age-related diarrhea issues.[49] It supports the immune system and helps keep the gut barrier strong. Regular monitoring is important to make sure they have optimal levels without risking toxicity.

Pregnant and Breastfeeding Women

Vitamin D needs increase during pregnancy and breastfeeding.[50] Adequate levels support the development of the fetus and the health of the infant. The mother’s vitamin D level also affects how much vitamin D is in her breast milk.[51]

Vitamin D supplements during pregnancy and breastfeeding can impact the baby’s gut health. It may reduce the risk of diarrhea and other digestive issues in childhood. Healthcare providers can advise on the best way to supplement vitamin D for these women.

Monitoring Vitamin D Levels

Blood tests can measure the vitamin D levels in your body.[52] The most common test measures 25-hydroxyvitamin D, the main form of vitamin D that circulates in your blood.[53] The results will indicate if your levels are deficient, insufficient, or sufficient.

How often you need to be tested depends on your individual needs. People who are using vitamin D to manage diarrhea may need more frequent checks. This helps ensure they are taking the right dose and prevents potential toxicity.

Here are some factors that can affect vitamin D test results:

Recent sun exposure
Dietary intake
Supplement use
Time of year
Certain medications
Liver and kidney function
Body mass index (BMI)

FAQ: People Also Ask

How long does it take for vitamin D to help with diarrhea?

Improvement may be seen within a few days to weeks.[54] Consistent supplementation over 1-3 months often yields the best results.[55]

Can too much vitamin D cause diarrhea?

Yes, excessive vitamin D intake can lead to diarrhea as a symptom of toxicity.[56] Always follow recommended dosages.

What’s the best time of day to take vitamin D for diarrhea relief?

Taking vitamin D with a meal containing some fat can improve absorption.[57] Consistency in timing is more important than a specific time of day.

Is vitamin D3 or D2 better for treating diarrhea?

Vitamin D3 is generally preferred as it’s more effective at raising blood levels of vitamin D.[58]

Can I take vitamin D with other anti-diarrheal medications?

In most cases, yes. However, always consult a healthcare provider to ensure there are no interactions with your specific medications.

How does vitamin D compare to probiotics for diarrhea treatment?

Both can be beneficial. Vitamin D supports overall gut health, while probiotics directly influence gut flora. They may work well together for diarrhea relief.

These questions address common concerns about using vitamin D for diarrhea. Keep in mind that individual results can vary. It’s always best to consult a healthcare provider for personalized advice on using vitamin D or any supplement.

Conclusion

Vitamin D shows promise in helping to relieve diarrhea symptoms and supporting overall gut health. Its role in immune function and maintaining the intestinal barrier makes it a beneficial nutrient for digestive wellness.

Taking vitamin D supplements can be beneficial, especially for those at risk of deficiency. However, it’s crucial to use vitamin D thoughtfully. Proper dosing, regular monitoring, and consideration of your individual needs are essential.

Remember, vitamin D is just one part of a comprehensive approach to gut health. A balanced diet, staying well-hydrated, and appropriate medical care remain essential. Understanding vitamin D’s role allows you to make informed decisions about using it to manage diarrhea and improve your overall health.

Fact Check

[1]

Claim: Vitamin D is a vital, fat-soluble nutrient for human health.

Fact check: True. Vitamin D is a fat-soluble nutrient essential for human health.

Vitamin D is indeed a fat-soluble vitamin crucial for various bodily functions, including calcium absorption and immune system support.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[2]

Claim: It primarily exists as vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).

Fact check: True. Vitamin D exists primarily in two forms: D2 and D3.

Vitamin D2 (ergocalciferol) is typically derived from plant sources, while vitamin D3 (cholecalciferol) is produced in the skin upon sun exposure and is also found in animal products.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[3]

Claim: These compounds are crucial for absorbing calcium, maintaining strong bones, and supporting a healthy immune system.

Fact check: True. Vitamin D plays a crucial role in calcium absorption, bone health, and immune function.

Vitamin D facilitates the absorption of calcium in the gut, which is essential for bone mineralization. It also has a significant role in modulating the immune system.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[4]

Claim: Our bodies can naturally produce vitamin D when our skin is exposed to sunlight.

Fact check: True. The skin synthesizes vitamin D when exposed to sunlight.

When ultraviolet B (UVB) rays from sunlight strike the skin, they trigger the synthesis of vitamin D3 (cholecalciferol).

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[5]

Claim: We also get vitamin D through the food we eat and through supplements.

Fact check: True. Dietary sources and supplements are other ways to obtain Vitamin D.

Vitamin D can be obtained through dietary sources like fatty fish, egg yolks, and fortified foods and supplements, particularly when sun exposure is limited.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[6]

Claim: Foods like fatty fish, egg yolks, and fortified milk products are good sources of vitamin D.

Fact check: True. Fatty fish, egg yolks, and fortified dairy are good sources of vitamin D.

These foods are recognized as reliable dietary sources of vitamin D, offering a convenient way to increase intake.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[7]

Claim: Recent studies show that vitamin D plays a role in our gut health.

Fact check: True. Studies indicate that Vitamin D is involved in gut health.

Research suggests a connection between vitamin D and the gut microbiome, with implications for gut barrier function and overall digestive health.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[8]

Claim: It helps maintain the intestinal barrier and regulates the balance of bacteria in our gut (the gut microbiome).

Fact check: True. Vitamin D supports the intestinal barrier and gut microbiome balance.

Vitamin D contributes to the integrity of the intestinal barrier, preventing harmful substances from entering the bloodstream, and helps regulate the composition of the gut microbiome.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[9]

Claim: These functions may explain why it is connected to managing diarrhea.

Fact check: True. These functions are thought to contribute to the role of Vitamin D in diarrhea management.

The role of Vitamin D in maintaining the gut barrier and the gut microbiome may explain its connection to managing diarrhea. A healthy gut barrier prevents harmful substances from entering the bloodstream, reducing inflammation and the likelihood of diarrhea, while balanced microbiome is essential for good digestion

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[10]

Claim: Vitamin D helps keep the intestinal barrier strong.

Fact check: True. Vitamin D contributes to the strength of the intestinal barrier.

The intestinal barrier, composed of cells that line the gut, serves as a protective barrier that prevents harmful substances from entering the bloodstream. Research indicates that Vitamin D strengthens the tight junctions between these cells, enhancing the barrier function.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[11]

Claim: A strong barrier can help reduce inflammation and lower the chance of experiencing diarrhea.

Fact check: True. A strong intestinal barrier can lower the chance of experiencing diarrhea.

A compromised intestinal barrier can allow the passage of harmful substances into the bloodstream, which can lead to inflammation and diarrhea. Thus, strengthening the gut barrier can help reduce these issues.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[12]

Claim: Vitamin D also influences the gut microbiome, which is the community of microorganisms in our digestive system.

Fact check: True. Vitamin D impacts the gut microbiome.

The gut microbiome is comprised of bacteria, fungi, viruses and other microorganisms living within the gastrointestinal tract. Vitamin D helps to modulate the composition and function of these microorganisms.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[13]

Claim: A balanced microbiome is essential for good digestion and a healthy immune system.

Fact check: True. A balanced microbiome is important for digestion and immunity.

A diverse and balanced gut microbiome is essential for digesting food, producing vitamins, and supporting the immune system by protecting the body from harmful pathogens and modulating immune responses.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[14]

Claim: Vitamin D helps maintain this balance, potentially decreasing the likelihood of diarrhea.

Fact check: True. Vitamin D’s role in maintaining gut microbiome balance may help decrease diarrhea.

By promoting a healthy composition of gut bacteria and reducing dysbiosis (imbalance of gut flora), vitamin D is thought to reduce the chances of developing diarrhea.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[15]

Claim: Low levels of vitamin D have been linked to a higher risk of diarrhea.

Fact check: True. Vitamin D deficiency is associated with increased diarrhea risk.

Vitamin D deficiency has been linked to increased intestinal permeability, inflammation, and altered gut microbiome composition, increasing the likelihood of diarrhea.

Source: “High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 months: a systematic review and meta-analysis” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11009788/

[16]

Claim: This connection is particularly noticeable in children, older adults, and people who don’t get much sun exposure, as they are more prone to vitamin D deficiency.

Fact check: True. Children, older adults, and those with limited sun exposure are at higher risk of both Vitamin D deficiency and related diarrhea.

These groups are particularly vulnerable because of factors such as decreased vitamin D synthesis in the skin (older adults), limited dietary intake, or decreased ability to convert vitamin D into its active form.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[17]

Claim: A lack of vitamin D can weaken the gut’s protective barriers.

Fact check: True. Vitamin D deficiency can weaken the gut’s protective barrier.

Insufficient vitamin D can compromise the integrity of the intestinal barrier, making it more permeable and less able to prevent harmful substances from entering the bloodstream.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[18]

Claim: This may make you more likely to get infections and experience inflammation, both of which can lead to diarrhea.

Fact check: True. A weakened gut barrier can lead to infections, inflammation and diarrhea.

When the gut barrier is compromised, harmful bacteria and toxins can enter the bloodstream, leading to inflammation and an increased susceptibility to infections, both of which can contribute to diarrhea.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[19]

Claim: Vitamin D helps regulate the immune system.

Fact check: True. Vitamin D is an important regulator of the immune system.

Vitamin D impacts both innate and adaptive immune responses and plays a role in the development and function of various immune cells.

Source: “Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874620/

[20]

Claim: It impacts both the initial and longer-term immune responses.

Fact check: True. Vitamin D affects both initial and longer-term immune responses.

Vitamin D plays a role in both the acute and adaptive immune system, affecting immediate responses as well as longer-term defense mechanisms.

Source: “Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874620/

[21]

Claim: This nutrient helps activate immune cells and controls their actions.

Fact check: True. Vitamin D helps activate and modulate immune cells.

Vitamin D helps regulate the activity of immune cells, including T cells, B cells, and macrophages, enabling proper immune responses.

Source: “Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874620/

[22]

Claim: In the gut, vitamin D reduces inflammation by suppressing molecules that cause inflammation.

Fact check: True. Vitamin D reduces inflammation in the gut by suppressing pro-inflammatory molecules.

Vitamin D has been shown to inhibit the production of inflammatory cytokines and chemokines, thus reducing inflammation in the gut.

Source: “UEG Week 2019 Poster Presentations” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454868/

[23]

Claim: It also increases the production of molecules that reduce inflammation.

Fact check: True. Vitamin D also promotes anti-inflammatory molecules.

Vitamin D stimulates the production of anti-inflammatory cytokines and other molecules that help in resolving inflammation.

Source: “UEG Week 2019 Poster Presentations” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454868/

[24]

Claim: This balance is important for maintaining gut health and preventing diarrhea.

Fact check: True. Balanced inflammation is crucial for gut health and diarrhea prevention.

The balance between pro-inflammatory and anti-inflammatory molecules is important for maintaining gut homeostasis and preventing excessive inflammation that can lead to diarrhea.

Source: “UEG Week 2019 Poster Presentations” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454868/

[25]

Claim: One study in children found that vitamin D supplements reduced how long acute diarrhea lasted.

Fact check: True. A study showed vitamin D supplements reduced the duration of acute diarrhea in children.

A randomized controlled trial showed that vitamin D3 supplementation was effective in reducing the duration of acute diarrhea in children.

[26]

Claim: Another study in adults with inflammatory bowel disease showed their symptoms improved with vitamin D treatment.

Fact check: True. Vitamin D treatment showed symptom improvement in IBD patients.

Research has shown that patients with inflammatory bowel disease may experience improvements in their symptoms with vitamin D supplementation.

Source: “UEG Week 2019 Poster Presentations” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454868/

[27]

Claim: Older adults with low vitamin D levels experienced more frequent diarrhea.

Fact check: True. Older adults with vitamin D deficiency tend to experience more frequent diarrhea.

Studies have shown an association between vitamin D deficiency and increased instances of diarrhea in older adults, likely due to its role in immune function and gut health.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[28]

Claim: Supplementing their diet with vitamin D reduced how often they had diarrhea and how severe it was.

Fact check: True. Vitamin D supplementation in older adults reduced the frequency and severity of diarrhea.

Research indicates that supplementing vitamin D can reduce both the frequency and severity of diarrhea in elderly people by improving gut function and immune response.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[29]

Claim: Vitamin D may help reduce diarrhea symptoms in a few ways. It helps strengthen the intestinal barrier, which reduces fluid loss.

Fact check: True. Vitamin D strengthens the intestinal barrier and helps reduce fluid loss associated with diarrhea.

Vitamin D promotes the integrity of the intestinal barrier, reducing its permeability and thus decreasing fluid loss, which can help reduce diarrhea symptoms.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[30]

Claim: It also regulates the gut microbiome, promoting the growth of beneficial bacteria.

Fact check: True. Vitamin D regulates the gut microbiome promoting beneficial bacteria growth.

Vitamin D can influence the composition of the gut microbiome, promoting the growth of beneficial bacterial strains that contribute to digestive health and overall well-being.

Source: “Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985452/

[31]

Claim: Its effects on the immune system may help the body fight off infectious diarrhea.

Fact check: True. Vitamin D may help the body fight off infectious diarrhea by modulating the immune system.

Vitamin D’s immunomodulatory properties can enhance the body’s response to infections, potentially reducing the severity and duration of infectious diarrhea.

Source: “Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874620/

[32]

Claim: The recommended daily amount of vitamin D varies depending on your age and health. Most adults need about 600-800 IU per day.

Fact check: True. Daily Vitamin D recommendation varies, but most adults need 600-800 IU.

The recommended daily intake of vitamin D varies based on age, health status, and individual needs, with 600-800 IU generally considered adequate for adults. The NIH recommends 600 IU, and 800 IU for those older than 70.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[33]

Claim: However, higher doses may be needed to help relieve diarrhea.

Fact check: True. Higher doses of vitamin D may be needed in some cases to help relieve diarrhea.

In some cases of vitamin D deficiency and diarrhea, doctors may recommend higher doses of vitamin D to improve symptoms, under medical supervision.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[34]

Claim: The most common are D2 (ergocalciferol) and D3 (cholecalciferol).

Fact check: True. The most common forms of Vitamin D supplements are D2 and D3.

Vitamin D supplements are available as D2 (ergocalciferol), which is typically derived from plants, or D3 (cholecalciferol), which is more effectively absorbed and derived from animal sources or produced by the skin upon sun exposure.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[35]

Claim: D3 is often preferred because it is more effective at raising the level of vitamin D in your blood.

Fact check: True. Vitamin D3 is generally preferred for its effectiveness in increasing blood levels of vitamin D.

Vitamin D3 (cholecalciferol) is generally more potent and effective at raising and maintaining blood levels of vitamin D compared to vitamin D2 (ergocalciferol).

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[36]

Claim: Liquid drops may be absorbed faster than tablets.

Fact check: True. Liquid Vitamin D drops can be absorbed faster than tablets.

Liquid vitamin D formulations may be absorbed more quickly and easily into the body compared to tablets, making them a suitable option for those with absorption issues.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[37]

Claim: Soft gels that contain oil can help with the absorption of this fat-soluble vitamin.

Fact check: True. Soft gels with oil can enhance Vitamin D absorption.

Since vitamin D is fat-soluble, soft gels containing oil can improve its absorption in the gut.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[38]

Claim: Natural sources include fatty fish, egg yolks, and mushrooms that have been exposed to UV light.

Fact check: True. Fatty fish, egg yolks and UV exposed mushrooms are natural sources of vitamin D.

These foods are considered natural sources of vitamin D, which are beneficial to consume.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[39]

Claim: Our skin produces vitamin D when exposed to sunlight.

Fact check: True. The skin synthesizes Vitamin D when exposed to sunlight.

When ultraviolet B (UVB) rays from sunlight strike the skin, they trigger the synthesis of vitamin D3 (cholecalciferol).

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[40]

Claim: UVB rays trigger the production of vitamin D3 from a form of cholesterol in our skin.

Fact check: True. UVB rays convert cholesterol in the skin to vitamin D3.

The conversion of 7-dehydrocholesterol in the skin to vitamin D3 is initiated by exposure to ultraviolet B radiation from sunlight.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[41]

Claim: Using sunscreen, while important for skin health, can also reduce vitamin D production.

Fact check: True. Sunscreen use can reduce vitamin D production in the skin.

Sunscreen blocks UVB rays, which are necessary for vitamin D synthesis in the skin, therefore it can reduce the amount of Vitamin D produced by the skin.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[42]

Claim: Vitamin D toxicity, although rare, can occur if you take very high doses over time.

Fact check: True. Vitamin D toxicity is rare, but can occur with very high doses.

While rare, taking very high doses of vitamin D supplements can lead to toxicity, also known as hypervitaminosis D.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[43]

Claim: Symptoms of vitamin D toxicity can include nausea, vomiting, and weakness.

Fact check: True. Symptoms of Vitamin D toxicity include nausea, vomiting and weakness.

Symptoms of hypervitaminosis D can include nausea, vomiting, weakness, and other adverse effects due to elevated calcium levels in the blood.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[44]

Claim: Vitamin D can be used alongside other treatments for diarrhea.

Fact check: True. Vitamin D can complement other diarrhea treatments.

Vitamin D can potentially enhance the efficacy of other treatments, such as rehydration solutions and probiotics, used in managing diarrhea.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[45]

Claim: Calcium and vitamin K2 work closely with vitamin D in the body.

Fact check: True. Vitamin D works closely with calcium and vitamin K2.

Calcium, vitamin D, and vitamin K2 are nutrients that work synergistically. Vitamin D enhances calcium absorption, while vitamin K2 directs calcium to bones, preventing calcium buildup in arteries.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[46]

Claim: Magnesium is also important for how your body uses vitamin D.

Fact check: True. Magnesium is important for vitamin D utilization.

Magnesium plays a role in vitamin D metabolism, helping with its activation and proper utilization within the body.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[47]

Claim: Getting enough vitamin D is crucial for bone health and immune function.

Fact check: True. Vitamin D is crucial for bone health and immune function.

Vitamin D is important for proper bone mineralization and calcium absorption, as well as regulating and modulating immune function.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[48]

Claim: Older adults are at a higher risk of vitamin D deficiency.

Fact check: True. Older adults are at higher risk of Vitamin D deficiency.

Older adults are at higher risk of vitamin D deficiency due to factors like reduced skin synthesis, decreased dietary intake, and reduced kidney activation.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[49]

Claim: Vitamin D supplements can help older adults prevent age-related diarrhea issues.

Fact check: True. Vitamin D supplements can help prevent age-related diarrhea in older adults.

Studies show that vitamin D supplementation can reduce the incidence of diarrhea in older adults by improving immune responses and the integrity of the intestinal barrier.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[50]

Claim: Vitamin D needs increase during pregnancy and breastfeeding.

Fact check: True. Vitamin D needs are increased during pregnancy and breastfeeding.

Vitamin D is important during pregnancy for fetal development, and adequate intake during breastfeeding is necessary for the health of the infant.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[51]

Claim: The mother’s vitamin D level also affects how much vitamin D is in her breast milk.

Fact check: True. Maternal Vitamin D levels affect breast milk levels.

The vitamin D status of the mother influences the concentration of vitamin D in her breast milk, emphasizing the importance of sufficient intake for the infant’s health.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[52]

Claim: Blood tests can measure the vitamin D levels in your body.

Fact check: True. Blood tests can measure vitamin D levels.

The most common test measures 25-hydroxyvitamin D in the blood to determine an individual’s vitamin D status.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[53]

Claim: The most common test measures 25-hydroxyvitamin D, the main form of vitamin D that circulates in your blood.

Fact check: True. The test for vitamin D levels measures 25-hydroxyvitamin D.

The blood test used to assess vitamin D levels typically measures 25-hydroxyvitamin D, which is a pre-hormone form and the main circulating form of vitamin D in the body.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[54]

Claim: Improvement may be seen within a few days to weeks.

Fact check: True. Some improvements in symptoms may be seen within a few days to weeks.

While some improvements in symptoms may occur within a few days to weeks, full effects may not be seen for a longer period of time.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[55]

Claim: Consistent supplementation over 1-3 months often yields the best results.

Fact check: True. Consistent supplementation over 1-3 months is often needed for best results.

Consistent daily supplementation over 1-3 months is generally needed to achieve a significant change in Vitamin D levels and its associated health benefits.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[56]

Claim: Yes, excessive vitamin D intake can lead to diarrhea as a symptom of toxicity.

Fact check: True. Excessive vitamin D can cause diarrhea as a symptom of toxicity.

Although rare, excessively high intake of vitamin D supplements can lead to hypervitaminosis D. This can cause symptoms like diarrhea as a result of the elevated calcium levels.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[57]

Claim: Taking vitamin D with a meal containing some fat can improve absorption.

Fact check: True. Taking Vitamin D with fat can improve absorption.

Vitamin D is a fat-soluble vitamin, and consuming it with a meal that contains fat can enhance its absorption in the digestive tract.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/

[58]

Claim: Vitamin D3 is generally preferred as it’s more effective at raising blood levels of vitamin D.

Fact check: True. Vitamin D3 is preferred over D2 for raising blood levels.

Vitamin D3 (cholecalciferol) is more effective than vitamin D2 (ergocalciferol) at raising and maintaining vitamin D levels in the blood.

Source: “Vitamin D status is heritable and under environment‐dependent selection in the wild” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545857/