Takeaways
- Collagen is the most abundant protein in the human body
- It provides structure and support to skin, joints, and tendons
- Collagen production naturally decreases with age
- Supplementation may help improve skin elasticity and joint health
- Diet and lifestyle factors can support natural collagen production
- More research is needed on long-term effects of collagen supplements
What is Collagen?
Collagen is a very common protein in the body. It is actually the most abundant protein we have. Think of collagen as the main building material for your body, like the “glue” holding together skin, bones, and other connective tissues.[1]
Your body makes collagen naturally. It does this by combining different amino acids, which are the basic building blocks of proteins. Key amino acids used to make collagen include glycine, proline, and hydroxyproline.[2]
There are at least 16 types of collagen, but most of the collagen in our bodies is one of three types: I, II, and III. Type I collagen is found in skin, bones, and tendons, Type II collagen is mainly in cartilage, and Type III collagen appears in skin, muscles, and blood vessels.[3]
Collagen forms strong, flexible fibers within the dermis, which is the layer beneath the surface of your skin. This fiber network provides support for your skin, allowing it to stretch and bounce back easily.[4]
As people get older, their bodies produce less collagen. Also, existing collagen tends to break down at a faster rate. This natural process is why wrinkles develop, skin sags, and joint cartilage weakens.[5]
The primary areas where collagen is produced or stored in your body include:
- Skin
- Bones
- Muscles
- Tendons
- Ligaments
- Blood vessels
- Corneas
Knowing how collagen functions in your body can help you make smart choices about the foods you eat, the supplements you might take, and how you care for your skin.[6]
Collagen Production in the Body
Your body naturally produces collagen using amino acids. This process takes place inside cells called fibroblasts, which are found in connective tissues throughout the body.[7]
Collagen production requires certain helper nutrients. Vitamin C is very important because it helps link amino acids together. This linkage process forms the collagen fibers.[8]
The amount of collagen your body makes slows as you age. This reduction in production typically starts in your 20s or 30s. After age 40, collagen production may decrease by about 1% each year, impacting skin, joints, and bones.[9]
Several things can impact collagen production, including:
- Age: As mentioned, production naturally decreases over time.
- Sun exposure: UV rays can damage collagen in the skin.
- Smoking: Tobacco use can interfere with collagen synthesis.
- Diet: Lack of nutrients can hinder collagen production.
- Stress: High stress levels may impact collagen formation.
To keep collagen levels healthy, it’s best to maintain a good lifestyle. This includes eating a balanced diet, protecting your skin from too much sun exposure, and avoiding smoking.[10]
| Nutrient | Function in Collagen Production |
|---|---|
| Vitamin C | Helps link amino acids in collagen synthesis |
| Proline | Amino acid used to form collagen |
| Glycine | Another key amino acid in collagen |
| Copper | Aids in collagen fiber formation |
| Zinc | Activates proteins necessary for collagen synthesis |
Understanding what affects collagen can help you support your body’s ability to make it naturally.[11]
Benefits of Collagen
Skin Health
Collagen is very important for skin health. It creates a fiber network in the dermis, which is deep within your skin. This network provides structure and keeps your skin elastic.[12]
When collagen levels drop as we age, skin loses firmness and elasticity, which results in wrinkles and sagging. Increasing collagen levels may help counter these signs of aging.[13]
Studies have found that collagen supplements may improve skin elasticity. For example, one study showed that women who took collagen peptides for 8 weeks had improved skin elasticity.[14]
Collagen helps skin hold onto moisture. This can make skin appear more hydrated and fuller. Research suggests that collagen supplements may help reduce dry skin.[15]
The visible skin improvements linked to collagen include:
- Improved elasticity
- Reduced wrinkles
- Better hydration
- Smoother texture
While people’s experiences can differ, many report that their skin looks better after using collagen supplements.[16]
Joint and Tendon Support
Collagen isn’t just beneficial for skin; it is also important for your joints and tendons. It is a main component of cartilage, which acts as a cushion within your joints.[17]
As you get older and your body produces less collagen, the cartilage in joints can become weaker. This can lead to stiffness and discomfort. Some research suggests collagen supplements may help with this.[18]
A review of different studies found that collagen supplements may reduce joint pain in people with osteoarthritis. Another study showed that athletes who took collagen had improved joint function.[19]
Collagen is also important for tendon strength. Tendons connect muscles to bones and must be strong and flexible. Collagen helps to ensure they have these qualities.[20]
Here’s how collagen helps to keep your joints healthy:
- Forms a major part of cartilage structure
- Helps maintain cartilage’s shock-absorbing properties
- Supports tendon strength and flexibility
- May reduce inflammation in joints
- Aids in joint lubrication
More research is still needed, but the existing evidence suggests that collagen can be good for the health of your joints and tendons.[21]
Bone Strength
Collagen is not just for skin and joints. It is also very important for your bones. About 90% of the protein in the bone matrix is collagen.[22]
Collagen creates a framework that holds calcium and other minerals in your bones. This framework gives bones their strength. As collagen decreases with age, bone density can also decline.[23]
Some research suggests that collagen supplements can help maintain bone health. A study of women past menopause found that collagen peptides increased their bone mineral density.[24]
Collagen works together with other nutrients in your bones. For instance, calcium and vitamin D work with collagen to help keep bones strong.[25]
The potential benefits of collagen for bone health include:
- Improved bone density
- Reduced risk of bone-related disorders
- Better bone strength and flexibility
Although collagen shows promise for bone health, it doesn’t replace the need for calcium and vitamin D. For good bone health, it is best to have a balanced approach.[26]
Collagen Supplementation
Types of Collagen Supplements
Collagen supplements are available in different forms. Understanding these can help you choose the one that best suits your needs.[27]
Hydrolyzed collagen is a common type, broken down into smaller peptides. This makes it easier for your body to absorb. It can be found in powders, capsules, or liquids.[28]
Collagen supplements typically come from animals. Bovine (cow) collagen is popular and contains types I and III collagen. Another choice is marine (fish) collagen, which is high in type I collagen.[29]
Here’s a breakdown of the different types of collagen and their main benefits:
| Collagen Type | Primary Source | Main Benefits |
|---|---|---|
| Type I | Bovine, Marine | Skin, hair, nails, bones |
| Type II | Chicken | Joints, cartilage |
| Type III | Bovine | Skin, blood vessels, organs |
Some supplements contain more than one type of collagen. This might give you a wider range of benefits.[30]
When you are selecting a supplement, think about your specific goals. For skin health, types I and III are often recommended, while type II may be more helpful for joint support.[31]
Effectiveness of Collagen Supplements
How well collagen supplements work is a common topic of research in nutrition. Some studies show positive results, but more research is still needed.[32]
Several studies suggest collagen supplements can improve skin elasticity and moisture. A review of 11 different studies found that taking collagen by mouth can increase skin elasticity and hydration.[33]
For joint health, the research is somewhat mixed but hopeful. Some studies show that taking collagen can reduce joint pain and improve how well joints function.[34]
How well collagen supplements work can depend on several factors, such as:
- Type of collagen
- Dosage
- Individual’s age and health status
- Diet and lifestyle factors
It’s important to have reasonable expectations. Collagen supplements are not a quick fix. However, they may offer some benefits when used as part of a healthy lifestyle.[35]
Conditions that may potentially benefit from collagen supplementation include:
- Skin aging
- Joint pain
- Osteoarthritis
- Wound healing
- Hair and nail health
Keep in mind that results can vary from one person to another. It is always best to talk with a doctor before starting any new supplement.[36]
Dietary Sources of Collagen
Although supplements are popular, you can also get more collagen through your diet. There are many foods that naturally contain collagen or help your body make it.[37]
Bone broth is a good source of collagen. It is made by cooking animal bones and connective tissues. This process helps extract collagen and other nutrients.[38]
Fish with edible bones, such as sardines and salmon, provide collagen. The skin of fish also contains collagen. Chicken, particularly with the skin, is another good source.[39]
Your body needs certain nutrients to create collagen. Vitamin C, for example, is essential for collagen production. Citrus fruits, berries, and leafy greens are good sources of vitamin C.[40]
Proline, an amino acid used to make collagen, is found in egg whites, dairy, cabbage, and mushrooms. Copper, which helps form collagen fibers, can be found in nuts and seeds.[41]
Here’s a list of the top foods that are rich in collagen or help boost collagen production:
- Bone broth
- Fish (especially with skin)
- Chicken (with skin)
- Egg whites
- Citrus fruits
- Berries
- Leafy greens
- Nuts and seeds
- Garlic
- Tomatoes
Eating a varied, nutrient-rich diet can support your body’s natural collagen production. This can work with collagen supplements, or be used on its own to help boost collagen.[42]
Collagen and Exercise
Exercise is good for more than just your muscles. It can also help with collagen health. Regular physical activity may help stimulate collagen production in your body.[43]
When you exercise, small tears develop in your muscle fibers. Your body repairs these tears using collagen. This process can cause increased collagen production over time.[44]
Some types of exercise may be particularly helpful for collagen production. For example, resistance training can stimulate collagen creation in tendons and ligaments.[45]
However, it’s important to not overdo it. Exercising too much can lead to collagen breakdown. Make sure to allow yourself enough time to recover between workouts.[46]
Here’s an example of an exercise routine that can support collagen production:
- Start with a 10-minute warm-up
- Perform 20-30 minutes of resistance training
- Include 15-20 minutes of low-impact cardio
- End with 10 minutes of stretching
- Rest for at least one day between workouts
This routine combines different types of exercise to help support overall collagen health. Always pay attention to your body and adjust as needed.[47]
Combining exercise with a diet that supports collagen can increase the benefits. Also, being well-hydrated is important for collagen health.[48]
Although exercise can help with collagen production, it’s not a replacement for a good diet or necessary supplements. It is best to have a well-rounded approach to health.[49]
Potential Side Effects and Considerations
While collagen supplements are generally considered safe, they can cause side effects in some people. It is important to know about these potential issues.[50]
Digestive problems are a common side effect. Some people report bloating or an upset stomach after taking collagen supplements.
Allergic reactions are possible, especially if you are allergic to fish or eggs. Many collagen supplements come from these sources.
Some people say that collagen supplements leave a bad taste in their mouth. This is more common with powdered supplements that are mixed into drinks.
Collagen supplements can interact with certain medications. For example, they may interfere with how your body absorbs some drugs.
Here are possible signs that your body is not tolerating collagen supplements:
- Nausea or stomach upset
- Bloating
- Diarrhea
- Skin rash or itching
- Headache
If you have any of these symptoms, stop taking the supplement and talk with your doctor.
It’s also important to know that dietary supplements aren’t as strictly regulated by the FDA as medications are. Always choose supplements from well-known, reliable manufacturers.
If you are pregnant or breastfeeding, you should talk with your doctor before taking collagen supplements. The same is true if you have existing health conditions.
While side effects are possible, many people take collagen supplements without any issues. Being informed can help you make good choices for your own health.
Choosing and Using Collagen Supplements
Choosing the right collagen supplement can be confusing because there are so many options. Here are some things to keep in mind when making your decision.
First, think about what you hope to gain. Are you trying to improve your skin, joints, or general well-being? Different types of collagen target different areas.
Check where the collagen comes from. Bovine, marine, and poultry are common sources. This is particularly important if you have dietary restrictions.
Look at the form of the supplement. Powders, capsules, and liquids are available. Powders are versatile, but might have a taste. Capsules are convenient, but might have a lower amount of collagen.
Check the additional ingredients. Some supplements include vitamin C or hyaluronic acid for extra benefits. Others might have unneeded fillers or additives.
Consider if the supplement has been tested by an independent third party. Some brands have their products tested by independent labs for purity and potency.
Here are some questions you should ask yourself when choosing a collagen supplement:
- What type of collagen does it contain?
- What’s the source of the collagen?
- How many grams of collagen per serving?
- Are there any additional active ingredients?
- Has it been third-party tested?
- Does it fit my dietary needs (e.g., gluten-free, non-GMO)?
Once you’ve selected a supplement, use it regularly for the best results. Most studies on collagen supplements lasted between 8 and 12 weeks.
The recommended amount to take can vary. Many studies used between 2.5 and 15 grams per day. Follow the instructions on the product or ask your doctor.
Some people prefer to take collagen in the morning, while others take it at night. There is no set best time. Choose a time that fits best with your daily schedule.
Keep in mind that supplements should be used in addition to a healthy diet and lifestyle, not instead of them. It may take weeks or months before you see a noticeable benefit.
Collagen in Skincare Products
Collagen is not just found in supplements. It is also a popular ingredient in skin care products. But how well does topical collagen actually work?
Most collagen molecules are too big to go deep into the skin. Instead, they usually work on the surface to provide moisture.
Some skin care products use hydrolyzed collagen. These smaller collagen peptides may be able to penetrate the skin more effectively. They can help improve skin moisture and texture.
Topical collagen products often contain other helpful ingredients. For instance, vitamin C can help increase collagen production in the skin.
While topical collagen can offer benefits, it doesn’t replace the natural collagen in your body. Using both topical and oral collagen may provide better results.
Popular skin care products containing collagen include:
- Moisturizers
- Serums
- Face masks
- Eye creams
- Body lotions
When choosing skin care products containing collagen, look for other ingredients that support skin health. Hyaluronic acid and peptides are good complements to collagen.
Remember that skin care is just one part of skin health. A balanced diet, proper hydration, and sun protection are also important for keeping your skin healthy.
Future of Collagen Research
Collagen research is an exciting area that is always growing. Scientists are exploring new ways to understand and use this important protein.
Recent studies have examined collagen’s potential beyond skin and joints. Some research suggests collagen may support heart health by improving how flexible the arteries are.
Another area being studied is collagen’s role in gut health. Some studies indicate that collagen may support the intestinal lining.
Researchers are also looking into new sources of collagen. Plant-based alternatives are especially interesting for those who follow vegan diets.
New technology is also emerging in collagen supplements. For example, some companies are working on making collagen more easily absorbed by the body.
While the current research is promising, there are many areas that need further study such as:
- Long-term effects of collagen supplementation
- Optimal dosages for different health goals
- Interactions between collagen and other nutrients
- Effectiveness of different collagen sources
- Impact of collagen on various health conditions
As the research continues, we may learn about even more ways collagen can be used to benefit health and well-being. It’s an exciting time for collagen science.
Remember, while research is ongoing, the current evidence supports collagen’s benefits for skin, joints, and bones. Always consult with your doctor for personalized advice.
FAQ
Maintaining a healthy lifestyle and protecting your skin from sun damage can help your body preserve its collagen.What does collagen do for your body?
How long does it take to see results from collagen supplements?
Can collagen help with weight loss?
Is it safe to take collagen every day?
What are the signs of collagen deficiency?
Does collagen help hair growth?
Can vegetarians get enough collagen?
What destroys collagen in the body?
Conclusion
Collagen is more than just a popular buzzword. It is a very important protein that plays a crucial role throughout your body. From helping skin stay elastic to keeping joints healthy and bones strong, collagen’s importance cannot be overstated.
As we’ve discussed, your body’s natural collagen production decreases as you age. This decline contributes to many signs of aging, including wrinkles, joint pain, and reduced bone density. While this process is natural, there are ways to support and potentially boost your collagen levels.
Collagen supplements have become popular and for good reason. Research suggests they may help with skin health, joint function, and bone strength. However, it’s important to be realistic about what they can do and to understand the current scientific findings.
Diet is also very important for collagen health. Eating foods rich in collagen or that help support its production can be an effective strategy. This approach not only helps collagen, but also contributes to overall health and well-being.
Exercise, especially resistance training, can help your body make more collagen. This highlights the importance of a well-rounded approach to health that includes both good nutrition and physical activity.
When it comes to skin care, topical collagen products can be helpful, particularly for moisturizing skin. However, they work best when used together with a complete skin care routine and healthy lifestyle habits.
As research in this area continues, we may learn about new uses and benefits of collagen. The future of collagen research is exciting with possible implications for gut health, heart health, and more.
Remember that while collagen supplements can be helpful, they aren’t a quick fix. They work best when used as part of a balanced diet, regular exercise, and a generally healthy lifestyle. Always talk to a doctor before starting any new supplement, especially if you already have health issues.
In conclusion, understanding collagen, its functions, benefits, and how to support its production empowers you to make good decisions about your health. Whether through diet, supplements, or lifestyle changes, supporting your body’s collagen can help you have healthier skin, stronger joints, and a better overall well-being as you age.
Collagen makes up about 30% of the body’s total protein. Its role as a ‘glue’ is an apt metaphor for its function in providing structure and support to various tissues.
Source: “Processing of collagen based biomaterials and the resulting materials properties” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423854/
These amino acids are crucial for the formation of collagen’s triple helix structure. Hydroxyproline is formed through the post-translational modification of proline and requires Vitamin C as a cofactor.
Source: “Processing of collagen based biomaterials and the resulting materials properties” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423854/
There are actually 28 known types of collagen. While types I, II, and III are dominant, other types have specialized functions in different tissues.
Source: “Processing of collagen based biomaterials and the resulting materials properties” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423854/
Collagen fibers are bundled together and arranged in a network that supports the skin’s structure, allowing it to resist deformation and return to its original shape. The dermis also contains elastin, which contributes to skin elasticity
Source: “Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11050892/
This is due to a variety of factors, including reduced fibroblast activity, increased collagenase activity (which breaks down collagen), and hormonal changes.
Source: “Aging impairs the osteocytic regulation of collagen integrity and bone quality” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897167/
This understanding empowers individuals to make informed choices about their diet, skincare routine, and supplementation, all aimed at supporting the body’s collagen production and maintenance.
Fibroblasts are the primary cell type involved in collagen synthesis. They are distributed throughout various connective tissues such as dermis, tendons, ligaments, and bone.
Source: “Expression of EMT-Related Genes in Hybrid E/M Colorectal Cancer Cells Determines Fibroblast Activation and Collagen Remodeling” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662237/
Vitamin C is essential for the enzymes that hydroxylate proline and lysine, enabling the formation of stable collagen triple helix structure. Without adequate vitamin C, collagen formation is impaired. Vitamin C is therefore an essential nutrient for connective tissue maintenance and repair.
Source: “SVCT2–mediated ascorbic acid uptake buffers stress responses via DNA hydroxymethylation reprogramming of S100 calcium-binding protein A4 gene” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694147/
The rate of decline varies among individuals, but the general trend is a continuous reduction over time, with more dramatic effects typically apparent after age 40. This leads to various age-related changes in tissues that rely on collagen.
Source: “Blueberry consumption prevents loss of collagen in bone matrix and inhibits senescence pathways in osteoblastic cells” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636388/
A balanced diet provides the necessary nutrients for collagen synthesis, sun protection prevents UV-induced collagen degradation, and avoiding smoking reduces collagen damage caused by free radicals and toxins.
This refers to understanding factors like diet, aging, and environmental exposures that influence collagen production and degradation to allow individuals to take informed actions to support their body’s collagen levels.
Collagen’s network in the dermis provides tensile strength, allowing skin to stretch without tearing. It also provides a scaffolding for other skin components. The loss of collagen as we age is a direct cause of wrinkles and saggy skin.
Source: “Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11050892/
The loss of collagen as we age reduces skin’s structural support and ability to recoil, which directly leads to the visible changes of wrinkles, fine lines and loss of firmness. Replenishing collagen may help restore some of this lost structure.
Source: “Research Progress in Skin Aging, Metabolism, and Related Products” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647560/
The bioavailability of hydrolyzed collagen peptides enables them to reach the dermis layer of the skin where they can exert their effects. Not all collagen supplements are created equal, and results may vary. More long-term research is needed.
Source: “Collagen supplementation in skin and orthopedic diseases: A review of the literature” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102402/
Collagen has hydrophilic properties which help retain water, improving skin hydration. This leads to more fullness, less wrinkling and reduces skin dryness, giving the skin a healthier appearance. Clinical studies have shown that supplementing collagen is effective for skin hydration.
Source: “Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180699/
Subjective user experiences of collagen supplementation can vary due to multiple factors including individual differences, product quality, dose, duration of intake, and lifestyle. Nevertheless, user feedback often includes improvements in skin smoothness, hydration, and overall appearance.
Collagen, especially type II, is a critical component of articular cartilage, providing its tensile strength and resilience, allowing it to function as a shock absorber and provide support for joints. Collagen in tendons provides flexibility and strength.
Source: “Collagen denaturation in post-run Achilles tendons and Achilles tendinopathy: In vivo mechanophysiology and magnetic resonance imaging” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11446262/
As collagen production declines, cartilage can lose its structural integrity, leading to reduced cushioning and increased joint stiffness and pain. Collagen supplementation may aid by providing the body with building blocks to help maintain and repair cartilage.
Source: “Impact of Specific Bioactive Collagen Peptides on Joint Discomforts in the Lower Extremity during Daily Activities: A Randomized Controlled Trial” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11203623/
A number of meta-analyses and studies have found that collagen supplements, especially hydrolyzed collagen, may offer pain relief and improve functionality, particularly in people with osteoarthritis and in athletes.
Source: “The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521576/
Tendons are composed of collagen fibers, which provide their tensile strength. Collagen provides the necessary structure for tendons to transmit the force of muscle contractions to bones. Adequate collagen is therefore essential for proper tendon function and injury prevention.
Source: “Collagen denaturation in post-run Achilles tendons and Achilles tendinopathy: In vivo mechanophysiology and magnetic resonance imaging” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11446262/
Current evidence suggests potential benefits, but further research with more participants is needed to establish more solid conclusions and fully understand the mechanisms by which collagen supplements help with joint and tendon health.
Collagen forms the organic framework of bone, upon which minerals like calcium are deposited. It’s primarily type I collagen. It gives bones their tensile strength, preventing them from being brittle.
Source: “Templated Three-Dimensional Engineered Bone Matrix as a Model for Breast Cancer Osteolytic Bone Metastasis Process” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727640/
The collagen network in bone provides the structural scaffold to hold calcium and other minerals. As collagen production declines with age, the mineral content in bone also decreases, which can lead to lower bone density and increased fracture risk. This is especially the case with post-menopausal women, where low estrogen levels reduce collagen synthesis.
Source: “The Effects of Claw Health and Bone Mineral Density on Lameness in Duroc Boars” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177061/
Studies have indicated that collagen supplementation may stimulate osteoblast differentiation (bone-building cells) and increase bone mineral density, particularly when combined with calcium and vitamin D supplementation. However, more long-term studies are needed.
Source: “Advanced glycation end products mediate biomineralization disorder in diabetic bone disease” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524989/
Calcium provides the mineral hardness to bone, while vitamin D regulates calcium absorption. Collagen is the structural protein upon which these minerals are deposited, giving bones their strength and preventing them from being brittle. Adequate intake of all three are essential.
Source: “The Effects of Different Dietary Patterns on Bone Health” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11280484/
A multi-faceted approach is crucial, as collagen, calcium, and vitamin D have distinct roles in bone health. Relying on any single component is inadequate for good bone health.
Collagen supplements are typically available in powders, capsules, liquids and gummies, each with their own pros and cons regarding taste, absorption, dosage, cost, and ease of use.
Hydrolyzed collagen is enzymatically broken into peptides of shorter chains of amino acids, which makes them easier to digest and absorb in the small intestine. It’s a common form in supplements due to its increased bioavailability.
Source: “Hydrolyzed collagen: Exploring its applications in the food and beverage industries and assessing its impact on human health – A comprehensive review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11381813/
Bovine collagen contains both type I and III and is popular for use in skin, bone and joint health. Marine collagen is typically derived from fish scales and skin and is predominantly type I.
Source: “A Comprehensive Analytical Approach for Quality Control of Collagen in Food Supplements” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509663/
Multi-collagen supplements aim to provide a broad spectrum of benefits by including more than one type of collagen from different sources. For example, they might include type I for skin and bones, type II for joint cartilage, and type III for skin and blood vessels.
Type I and III collagen are most abundant in skin, making them ideal for addressing skin health. Type II collagen is predominant in cartilage making it most useful for joint issues. This helps consumers choose the most appropriate collagen type for their individual health goals.
Collagen supplements are not currently regulated, therefore it’s an ongoing process to establish more long-term clinical results and how to optimize their benefits. More studies are needed to confirm and refine the current scientific understanding.
Source: “A Comprehensive Analytical Approach for Quality Control of Collagen in Food Supplements” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11509663/
A number of meta-analyses and systematic reviews of clinical trials have shown that taking collagen supplements, specifically hydrolyzed collagen, can improve skin elasticity, hydration, and appearance.
Source: “Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180699/
While many studies have reported positive outcomes with collagen for reducing joint pain and improving function, particularly in people with osteoarthritis, some trials have yielded inconsistent findings. More robust, long-term clinical trials are needed to establish more solid conclusions.
Collagen supplements are best used in conjunction with a good diet, exercise routine and skincare. They are not a substitute for healthy habits, and results are typically only seen after consistent use over several weeks or months.
Individual factors like age, genetics, pre-existing health conditions, diet, and lifestyle can affect the way someone may respond to collagen supplementation. It’s best to consult with a healthcare professional to understand if collagen supplementation is appropriate and safe.
Diet is vital in providing building blocks and supporting collagen production. Both dietary collagen and nutrients necessary for the body to make it are important, highlighting a holistic approach to collagen health.
During the process of slow cooking bones, the collagen in the connective tissue is broken down into gelatin, which is a form of collagen. Bone broth is also a good source of minerals and amino acids
Source: “Development of Biodegradable Osteopromotive Citrate-based Bone Putty” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463100/
Fish skin, bones and scales are particularly rich in collagen. Chicken skin and bone are also rich in collagen. Consuming these food sources is one way to obtain dietary collagen.
Source: “Significant Amounts of Functional Collagen Peptides Can Be Incorporated in the Diet While Maintaining Indispensable Amino Acid Balance” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566836/
Vitamin C is essential for the hydroxylation of proline and lysine, which are necessary for the crosslinking of collagen fibers. It acts as a cofactor for the enzymes responsible for stable collagen formation. Citrus fruits, berries, and leafy greens are good sources of dietary Vitamin C.
Source: “SVCT2–mediated ascorbic acid uptake buffers stress responses via DNA hydroxymethylation reprogramming of S100 calcium-binding protein A4 gene” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694147/
Proline is a key amino acid for collagen structure, and egg whites, dairy, cabbage, and mushrooms are all good sources. Copper is a cofactor for enzymes involved in collagen formation, and nuts and seeds are dietary sources.
Source: “Copper catalyzed Shono-type oxidation of proline residues in peptide” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10881060/
A diet rich in collagen, amino acids, vitamin C, and minerals provides the necessary building blocks for the body’s natural collagen synthesis. Eating a balanced diet can support collagen health on its own or work alongside collagen supplements.
Exercise places mechanical stress on connective tissues, which stimulates fibroblasts to produce more collagen. This is particularly true with weight training which places a greater demand on tendons and ligaments.
Source: “The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521576/
Microtears that happen during exercise trigger the body’s repair mechanisms, which includes producing new collagen to rebuild muscles and other connective tissues. This adaptive response is a normal part of exercise and leads to increased collagen over time.
Source: “Bioactive materials for in vivo sweat gland regeneration” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457517/
Weight training is an effective way to apply mechanical stress to tendons, ligaments and muscles, which triggers fibroblasts to produce new collagen, helping to strengthen these tissues.
Source: “The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521576/
Over-exertion can lead to excessive tissue damage, which can stimulate inflammation and collagen degradation. Adequate rest and recovery are essential for proper collagen repair and synthesis.
Source: “Collagen Protein Ingestion during Recovery from Exercise Does Not Increase Muscle Connective Protein Synthesis Rates” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487367/
A balance of different exercise types is optimal for overall health, but should be adjusted based on individual tolerance. This includes both resistance training, which stimulates collagen synthesis, and cardio which is beneficial for overall health, and can support blood flow for the transportation of nutrients for collagen synthesis.
The combination of exercise, a collagen-supporting diet, and hydration provides the body with the stimulation, building blocks, and environment for optimal collagen synthesis and function. Exercise stimulates collagen synthesis, a collagen-rich diet provides the building blocks, and adequate hydration ensures the proper cellular processes occur
Exercise is beneficial for overall health and stimulates collagen production, but adequate nutrition is still essential. A balanced diet provides the amino acids, vitamins and minerals needed for collagen synthesis, which exercise alone cannot provide. Similarly, collagen supplements can provide additional collagen and are a viable approach when dietary sources are not sufficient
While generally considered safe, individuals may react differently to supplements. Understanding potential issues helps people make informed decisions. It’s best to discuss any concerns with a healthcare provider.
