Table of Contents

Lemon Balm: Potential Side Effects

Takeaways

  • Lemon balm can cause drowsiness and sedation
  • It may interact with thyroid medications
  • Gastrointestinal issues are possible side effects
  • Long-term safety data is limited
  • Proper dosing is essential to minimize risks
  • Consult a doctor before use, especially if pregnant

What is Lemon Balm?

Lemon balm, scientifically known as Melissa officinalis, is a member of the mint family.[1] This herb is native to regions including Europe, North Africa, and West Asia.[2] For many centuries, people have used lemon balm in traditional medicine practices.

Lemon balm is characterized by its distinct lemony scent and flavor.[3] The plant’s leaves are oval-shaped with toothed edges, and it produces small white flowers.[4] It’s known to grow easily in a variety of climates and garden settings.[5]

Traditionally, herbalists have valued lemon balm for its perceived calming properties.[6] It has been used to help reduce anxiety, promote restful sleep, and support healthy digestion.[7] Recent research into its potential benefits has increased modern interest in lemon balm.[8]

Today, lemon balm is available in several different forms.

  • Dried leaves for tea
  • Liquid extracts
  • Capsules and tablets
  • Essential oils
  • Topical creams

Chemical Composition

Lemon balm contains a variety of active chemical compounds.[9] These substances are believed to be responsible for the herb’s effects on both the body and mind.[10]

The primary groups of chemical compounds found in lemon balm are:

  • Terpenes
  • Flavonoids
  • Phenolic acids
Compound Potential Effects
Rosmarinic acid Antioxidant, anti-inflammatory
Citral Antimicrobial, calming
Eugenol Pain-relieving, antispasmodic
Geraniol Antiviral, insect-repelling

These compounds are thought to work in combination to produce lemon balm’s effects. For instance, rosmarinic acid may help to lessen inflammation.[11] Citral, on the other hand, is believed to contribute to the herb’s calming qualities.[12]

The precise chemical makeup of lemon balm can differ based on factors such as growing conditions and the methods used to process it.[13] These variations can have an impact on the potency and resulting effects of lemon balm products.[14]

Potential Benefits

Lemon balm has become popular due to its potential health benefits. Current research indicates that it might be helpful for several health concerns.

Anxiety and stress relief are often cited as key benefits of lemon balm use.[15] Many individuals find that lemon balm helps them to feel more relaxed. Studies suggest it may reduce the symptoms of mild anxiety.[16]

Lemon balm might also aid in improving sleep quality.[17] Some individuals report experiencing quicker sleep onset and more restful sleep. Research studies have provided some support for these claims, showing improvements in sleep patterns for some users.[18]

The potential cognitive benefits of lemon balm are also being studied. Preliminary research indicates that it may improve memory and concentration.[19] These effects appear to be most prominent in older adults.[20]

Other potential benefits associated with lemon balm include:

  • Digestive support
  • Headache relief
  • Antiviral properties
  • Mood improvement
  • Menstrual cramp relief

While these potential benefits are encouraging, more studies are needed. Many of the current studies are either small-scale or use animal subjects.[21] Larger trials involving human participants would provide more robust evidence.[22]

Common Side Effects

Like any herb, lemon balm can cause side effects in some people. The majority of these side effects are mild and tend to be short-lived.[23]

Gastrointestinal problems are among the most frequently reported side effects. Some users have experienced:

These digestive symptoms are more likely to occur with higher doses or in people who have sensitive digestive systems.[24]

Drowsiness and sedation are also potential side effects.[25] Because lemon balm has calming properties, some individuals might find these effects to be too strong. This drowsiness can interfere with routine activities, such as driving.[26]

Skin reactions are possible, particularly with topical applications of lemon balm. Some individuals may experience:

  • Redness
  • Itching
  • Rash

Allergic reactions, while infrequent, can happen.[27] Those who are allergic to other plants in the mint family should be cautious when using lemon balm.[28]

Other minor side effects that have been reported include:

  • Headache
  • Dizziness
  • Increased appetite
  • Wheezing (in high doses)

Most side effects tend to resolve on their own once the use of lemon balm is discontinued.[29] Lowering the dose often helps in lessening these side effects.[30]

Serious Side Effects

Although rare, some individuals have experienced more serious side effects from using lemon balm. These more serious effects require prompt medical attention.

One significant concern is the potential for interference with thyroid function.[31] Lemon balm may affect the body’s levels of thyroid hormones.[32] This could be particularly dangerous for people who have existing thyroid conditions.[33]

Another serious risk involves potential drug interactions. Lemon balm can interact with several medications such as:

  • Sedatives
  • Thyroid medications
  • Some HIV medications
  • Certain diabetes drugs

These interactions could potentially lead to amplified side effects or reduce the intended effectiveness of the medications.[34]

Pregnant and breastfeeding women should use caution with lemon balm.[35] There isn’t enough reliable research to confirm its safety during pregnancy or breastfeeding.[36]

If you experience serious side effects, it is important to:

  1. Stop using lemon balm immediately
  2. Contact your healthcare provider
  3. Seek emergency care if symptoms are severe
  4. Report the reaction to the FDA or relevant authority
  5. Keep the product for potential testing

It’s crucial to inform your doctor about any herbal supplements you are taking.[37] This information can help prevent harmful interactions with other medications or treatments.

Dosage and Administration

The correct dosage of lemon balm is important for safe use. The appropriate dose depends on several factors.[38]

Typical dosage guidelines vary based on the form of lemon balm used:

  • Tea: 1.5 to 4.5 grams of dried herb per cup, up to 4 times daily
  • Capsules: 300 to 1200 mg daily, divided into 2-3 doses
  • Liquid extract: 60 to 180 drops daily, divided into 2-3 doses
Form Typical Dose Max Daily Dose
Tea 1.5-4.5g/cup 4 cups
Capsules 300-1200mg 1200mg
Liquid Extract 60-180 drops 180 drops

Factors that can influence the appropriate dosage of lemon balm include:

  • Age
  • Weight
  • Overall health
  • Specific condition being treated

For safe use of lemon balm, remember to:

  • Start with a low dose
  • Increase gradually if needed
  • Don’t exceed recommended amounts
  • Take breaks from use periodically
  • Consult a healthcare provider for personalized advice

Keep in mind that taking more is not always better.[39] Higher doses of lemon balm can increase your risk of side effects.[40]

Drug Interactions

Lemon balm may interact with various types of medications.[41] These interactions can alter how these drugs function within the body.

Sedatives and sleep aids are a primary concern for interactions. Lemon balm might intensify the effects of these medications. This combination can cause excessive drowsiness. Examples include:

  • Benzodiazepines
  • Barbiturates
  • Zolpidem (Ambien)

Lemon balm may also interact with thyroid medications.[42] The herb may interfere with the body’s use of thyroid hormones.[43] This could make thyroid medications less effective.

Other types of medications that may interact with lemon balm include:

  • HIV protease inhibitors
  • Glaucoma medications
  • Cholinergic drugs
  • Some antidepressants

To avoid the possibility of dangerous interactions, it’s crucial to:

  • Tell your doctor about all supplements you take
  • Don’t combine lemon balm with sedatives
  • Avoid use before surgery
  • Check with a pharmacist before starting new medications
  • Monitor for unusual effects when combining supplements

It’s always best to be extra cautious when considering the potential for interactions between herbal supplements and prescription medications.

Precautions and Contraindications

Some individuals should avoid lemon balm altogether or use it with extreme caution. Certain pre-existing health conditions increase the risk of adverse side effects.

People with thyroid disorders should be especially careful when considering lemon balm.[44] The herb can interfere with thyroid function, which could worsen existing conditions or make treatments less effective.

Individuals scheduled for surgery should discontinue lemon balm use.[45] The herb can potentially enhance the effects of anesthesia.[46] This interaction may lead to complications during the surgery.

Other conditions where caution is advised include:

  • Diabetes (may affect blood sugar)
  • Glaucoma (may increase eye pressure)
  • Anxiety disorders (may worsen symptoms in some cases)
  • Pregnancy and breastfeeding (due to lack of safety data)

Before beginning lemon balm supplementation, it’s important to:

  1. Consult with a healthcare provider
  2. Review your current medications and supplements
  3. Discuss your medical history and any existing conditions
  4. Consider alternatives if you have contraindications
  5. Start with a low dose if approved for use

Taking these precautions will help to make sure that lemon balm is a safe choice for your particular situation.

Quality and Safety Considerations

The quality of lemon balm products significantly influences both their safety and effectiveness. The dietary supplement industry has less stringent oversight, which can lead to variability in product quality.[47]

The lack of strict regulation allows for some lower quality products to be available on the market. The Food and Drug Administration (FDA) does not approve herbal supplements before they go on sale.[48] They only take action if problems surface after a product has been marketed.

Some lemon balm products may contain contaminants or adulterants, which pose safety risks. These may include:

  • Heavy metals
  • Pesticides
  • Microbes
  • Undeclared ingredients

Third-party testing is one way to help confirm product quality. Look for certifications from independent organizations like:

  • USP (United States Pharmacopeia)
  • NSF International
  • ConsumerLab

To select high-quality lemon balm products, consider the following guidelines:

  • Buy from reputable sources
  • Look for standardized extracts
  • Check for third-party certifications
  • Read product labels carefully
  • Avoid products with outlandish claims

Quality is very important for both safety and product effectiveness. Do not sacrifice product quality when choosing lemon balm supplements.

Long-term Use and Tolerance

The safety and effectiveness of long-term lemon balm use are not fully understood.[49] Research on extended use is still limited.

Tolerance may develop with regular daily use over long periods.[50] This might mean you need to take higher doses to achieve the same effect. Developing a tolerance may also increase the risk of adverse side effects.

Long-term safety data is currently lacking.[51] The majority of studies primarily examine short-term use. The potential risks of consumption over many years are not fully known.

Some experts advise cycling lemon balm use.[52] This means taking periodic breaks from taking the herb. This strategy may help to prevent tolerance and reduce any unknown risks from long-term use.

If you plan to use lemon balm for an extended time, consider these recommendations:

  1. Consult a healthcare provider regularly
  2. Monitor for changes in effectiveness
  3. Take periodic breaks from use
  4. Use the lowest effective dose
  5. Stay informed about new research

Remember that ‘natural’ does not automatically mean safe for long-term use.[53] It’s wise to be cautious with any supplement that is used over an extended time.

Comparing Lemon Balm to Other Herbs

Lemon balm shares some similar qualities with other herbs that have calming effects. Comparing these herbs will help you choose the most suitable option.

Chamomile is another herb frequently compared to lemon balm for its relaxing effects. Both herbs are known for their calming properties. Chamomile tends to be gentler and less likely to cause drowsiness, while lemon balm may be more effective for managing anxiety.[54]

Valerian is another herb that is used to support sleep. It is generally stronger than lemon balm. Valerian may cause more side effects, including vivid dreams.[55] Lemon balm provides milder sleep support with fewer risks of side effects.

Herb Main Use Strength Side Effect Risk
Lemon Balm Anxiety, Sleep Moderate Low to Moderate
Chamomile Relaxation Mild Very Low
Valerian Sleep Strong Moderate
Passionflower Anxiety Moderate Low

Combining lemon balm with other supplements is common. Some common combinations include:

  • Lemon balm and chamomile for enhanced relaxation
  • Lemon balm and valerian for stronger sleep support
  • Lemon balm and passionflower for anxiety relief

It’s always best to research any combinations before trying them. Some herbs may interact or have additive effects, which may not be desirable.[56]

FAQ

Can lemon balm cause liver damage?
There’s no evidence that lemon balm causes liver damage in normal doses.[57] However, very high doses might stress the liver.[58] People with liver conditions should consult a doctor before use.

Is it safe to take lemon balm every day?
Short-term daily use appears safe for most people.[59] Long-term daily use lacks research.[60] It’s wise to take breaks or cycle use to prevent potential tolerance or unknown effects.

Does lemon balm interact with antidepressants?
Lemon balm may interact with some antidepressants, especially SSRIs.[61] It could increase drowsiness or affect how the body processes the medication.[62] Always consult your doctor before combining lemon balm with antidepressants.

Can lemon balm make anxiety worse?
While rare, some people report increased anxiety with lemon balm.[63] This effect might be due to individual sensitivity or interactions with other medications. If anxiety worsens, stop use and consult a healthcare provider.[64]

How long does it take for lemon balm to work?
Effects can vary. For anxiety or stress relief, some people feel results within 30 minutes.[65] For sleep benefits, it may take a few hours.[66] Consistent use over several weeks may be needed for full effects.[67]

Is lemon balm addictive?
Lemon balm is not considered addictive.[68] However, people may become psychologically dependent on its calming effects.[69] It’s always best to use herbal supplements as part of a broader health strategy, not as a sole solution.

These questions highlight some common concerns about the potential side effects of lemon balm. Always keep in mind that individual responses to herbal supplements can vary. What works effectively for one person may not have the same result for another.

If you are unsure, it is always best to seek personalized guidance from a qualified healthcare professional. They can assess your specific health conditions and needs.

Conclusion

Lemon balm has potential benefits for anxiety, sleep issues, and cognitive function. It’s historical use and the findings of current research support the popularity of this herb.

However, just like any supplement, lemon balm comes with potential risks. Side effects, although typically mild, can occur. Drug interactions and effects on thyroid function are serious considerations for some individuals.

To use lemon balm safely:

  • Start with low doses
  • Be aware of potential side effects
  • Inform your healthcare providers
  • Choose high-quality products
  • Avoid use if you have contraindications

Lemon balm may be a helpful tool for many people; however, it is not a risk-free option, and it is not a cure for any underlying condition. Use it wisely as part of a comprehensive approach to health.

Remember that herbal supplements are not meant to replace medical treatment. They should supplement a healthy lifestyle. Always seek professional medical advice for any persistent health concerns.

Stay well-informed, listen to your body, and make choices that support your overall well-being. When used carefully, lemon balm may offer benefits without undue risks.

Fact Check
Claim: Lemon balm, scientifically known as Melissa officinalis, is a member of the mint family.
Fact check: True. Lemon balm is classified within the mint family (Lamiaceae).

The botanical classification of lemon balm places it firmly within the mint family, characterized by its aromatic leaves and square stems.

Source: “Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998931/

Claim: This herb is native to regions including Europe, North Africa, and West Asia.
Fact check: True. Lemon balm is native to Europe, North Africa, and West Asia.

The natural range of lemon balm includes the Mediterranean region, extending into parts of Europe, North Africa, and West Asia, although it has been introduced to other areas.

Source: “Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998931/

Claim: Lemon balm is characterized by its distinct lemony scent and flavor.
Fact check: True. Lemon balm is well-known for its characteristic lemony aroma and taste.

The presence of compounds like citral contribute to the lemon-like scent and flavor of lemon balm, distinguishing it from other mint family members.

Source: “Melissa officinalis L. as a Sprout Suppressor in Solanum tuberosum L. and an Alternative to Synthetic Pesticides” https://pubmed.ncbi.nlm.nih.gov/36306427/

Claim: The plant’s leaves are oval-shaped with toothed edges, and it produces small white flowers.
Fact check: True. Lemon balm leaves are oval with toothed edges and it produces small white flowers.

These are characteristic morphological features of the lemon balm plant.

Claim: It’s known to grow easily in a variety of climates and garden settings.
Fact check: True. Lemon balm is known for its adaptability and ease of cultivation.

Lemon balm is known to grow in a variety of conditions, preferring well-drained soil and partial shade, however it is known to be very versatile and adapt well.

Claim: Traditionally, herbalists have valued lemon balm for its perceived calming properties.
Fact check: True. Lemon balm has a long history of traditional use for its calming effects.

Historical use of lemon balm in traditional medicine is well documented, with primary focus on its ability to reduce anxiety and promote relaxation.

Source: “Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998931/

Claim: It has been used to help reduce anxiety, promote restful sleep, and support healthy digestion.
Fact check: True. Traditional uses of lemon balm include reducing anxiety, aiding sleep, and supporting digestion.

These are the main areas where lemon balm has been traditionally used in herbal medicine.

Source: “Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998931/

Claim: Recent research into its potential benefits has increased modern interest in lemon balm.
Fact check: True. Current scientific studies are exploring the traditional uses of lemon balm, increasing interest.

Modern research is focused on validating traditional claims and investigating the chemical compounds responsible for these effects.

Source: “Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998931/

Claim: Lemon balm contains a variety of active chemical compounds.
Fact check: True. Lemon balm contains a complex mixture of chemical compounds.

These include essential oils, flavonoids, phenolic acids and terpenes.

Source: “Melissa officinalis L. as a Sprout Suppressor in Solanum tuberosum L. and an Alternative to Synthetic Pesticides” https://pubmed.ncbi.nlm.nih.gov/36306427/

Claim: These substances are believed to be responsible for the herb’s effects on both the body and mind.
Fact check: True. The chemical compounds are thought to be responsible for lemon balm’s effects.

The various compounds in lemon balm are thought to work together synergistically to produce its therapeutic effects.

Source: “Melissa officinalis L. Aqueous Extract Exerts Antioxidant and Antiangiogenic Effects and Improves Physiological Skin Parameters” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073307/

Claim: For instance, rosmarinic acid may help to lessen inflammation.
Fact check: Potentially True. Rosmarinic acid has shown anti-inflammatory effects in studies.

Rosmarinic acid is a phenolic compound found in lemon balm that has demonstrated some anti-inflammatory activity.

Source: “Rosmarinic Acid: A Potential Therapeutic Agent in Gastrointestinal Cancer Management—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546295/

Claim: Citral, on the other hand, is believed to contribute to the herb’s calming qualities.
Fact check: Potentially True. Citral has shown some calming effects in studies, but more research is needed.

Citral is a component of lemon balm’s essential oil. Preliminary studies support some sedative and anti-anxiety effects.

Source: “Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998931/

Claim: The precise chemical makeup of lemon balm can differ based on factors such as growing conditions and the methods used to process it.
Fact check: True. The chemical composition of lemon balm is variable based on several factors.

Environmental factors like climate, soil composition, and processing methods can all influence the levels of active compounds in lemon balm.

Source: “Comparative Studies on the Anti-Inflammatory and Apoptotic Activities of Four Greek Essential Oils: Involvement in the Regulation of NF-κΒ and Steroid Receptor Signaling” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381560/

Claim: These variations can have an impact on the potency and resulting effects of lemon balm products.
Fact check: True. Variability in chemical composition can lead to differences in product potency.

Variations in the chemical profile of lemon balm can result in products with differing levels of therapeutic compounds, potentially leading to inconsistent results.

Source: “Comparative Studies on the Anti-Inflammatory and Apoptotic Activities of Four Greek Essential Oils: Involvement in the Regulation of NF-κΒ and Steroid Receptor Signaling” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381560/

Claim: Anxiety and stress relief are often cited as key benefits of lemon balm use.
Fact check: True. Lemon balm is often cited for its potential to reduce anxiety and stress.

Many people use lemon balm as a natural remedy for stress and mild anxiety, this is also the most common use traditionally.

Source: “Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998931/

Claim: Studies suggest it may reduce the symptoms of mild anxiety.
Fact check: Potentially True. Some studies suggest lemon balm can alleviate mild anxiety symptoms.

Clinical trials investigating the anxiolytic effects of lemon balm have shown some positive results in reducing mild anxiety symptoms, but more research is needed.

Source: “The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis” https://pubmed.ncbi.nlm.nih.gov/34449930/

Claim: Lemon balm might also aid in improving sleep quality.
Fact check: Potentially True. Some evidence suggests lemon balm may help with sleep quality.

Preliminary studies and some clinical research point towards improvements in sleep quality and duration with lemon balm use.

Source: “The effect of probiotics on mood and sleep quality in postmenopausal women: A triple-blind randomized controlled trial” https://pubmed.ncbi.nlm.nih.gov/35871917/

Claim: Research studies have provided some support for these claims, showing improvements in sleep patterns for some users.
Fact check: Potentially True. Some studies suggest that lemon balm improves sleep patterns for some users.

While research on lemon balm and sleep is ongoing, some studies have shown evidence of improved sleep onset and quality.

Source: “The effect of probiotics on mood and sleep quality in postmenopausal women: A triple-blind randomized controlled trial” https://pubmed.ncbi.nlm.nih.gov/35871917/

Claim: Preliminary research indicates that it may improve memory and concentration.
Fact check: Potentially True. Preliminary research suggests lemon balm could enhance cognitive function.

Some studies suggest lemon balm may have beneficial effects on cognition, including memory and concentration.

Source: “Antiviral Potential of Melissa officinalis L.: A Literature Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841880/

Claim: These effects appear to be most prominent in older adults.
Fact check: Potentially True. Some studies suggest that the cognitive effects of lemon balm are more prominent in older adults.

Some trials show improved cognitive functions in older adults. However, additional research is needed to solidify these claims and the underlying mechanisms.

Source: “Antiviral Potential of Melissa officinalis L.: A Literature Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841880/

Claim: Many of the current studies are either small-scale or use animal subjects.
Fact check: True. A lot of the current research is limited due to small sample sizes or animal subjects.

While there is promise from current research, more large scale human trials are needed for full evidence.

Claim: Larger trials involving human participants would provide more robust evidence.
Fact check: True. Larger human trials are needed to confirm many benefits of lemon balm.

Many potential benefits require further investigation with large-scale clinical trials with human participants.

Claim: The majority of these side effects are mild and tend to be short-lived.
Fact check: True. Most reported side effects of lemon balm are mild and temporary.

Side effects like digestive upset and drowsiness tend to resolve quickly and are generally not severe.

Claim: These digestive symptoms are more likely to occur with higher doses or in people who have sensitive digestive systems.
Fact check: True. Digestive symptoms are often dose-dependent or more common in those with sensitive systems.

Higher doses may cause stomach upset, bloating or nausea in some people, especially those with digestive issues.

Claim: Drowsiness and sedation are also potential side effects.
Fact check: True. Lemon balm may cause drowsiness or sedation in some individuals.

Lemon balm’s calming properties may lead to drowsiness, particularly if taken in higher doses, or in combination with other sedatives.

Claim: This drowsiness can interfere with routine activities, such as driving.
Fact check: True. Drowsiness caused by lemon balm may impair activities requiring alertness.

It is important to exercise caution when operating machinery or driving after taking lemon balm due to its potential to cause drowsiness.

Claim: Allergic reactions, while infrequent, can happen.
Fact check: True. Allergic reactions to lemon balm are possible, although rare.

Allergic responses such as skin rash, itching, or hives are possible but not common.

Claim: Those who are allergic to other plants in the mint family should be cautious when using lemon balm.
Fact check: True. People with mint allergies should be cautious when using lemon balm.

Individuals with known allergies to other plants in the mint family (Lamiaceae) may also be more likely to react to lemon balm.

Claim: Most side effects tend to resolve on their own once the use of lemon balm is discontinued.
Fact check: True. Side effects typically subside with discontinuation of lemon balm use.

Most side effects associated with lemon balm are temporary and resolve when use is stopped.

Claim: Lowering the dose often helps in lessening these side effects.
Fact check: True. Reducing the dosage of lemon balm can often alleviate side effects.

Adjusting the amount of lemon balm taken can often decrease the chance of side effects such as digestive issues or drowsiness.

Claim: One significant concern is the potential for interference with thyroid function.
Fact check: Potentially True. Lemon balm may interfere with thyroid function, but more research is needed.

There is some preliminary evidence that lemon balm may impact thyroid hormone levels. This is a concern for those with pre-existing thyroid conditions.

Claim: Lemon balm may affect the body’s levels of thyroid hormones.
Fact check: Potentially True. Lemon balm may influence thyroid hormone levels.

Animal models and limited human studies suggest lemon balm may affect thyroid hormone production or metabolism. However, more human research is needed.

Claim: This could be particularly dangerous for people who have existing thyroid conditions.
Fact check: True. People with thyroid conditions need to be especially cautious when using lemon balm.

The potential impact on thyroid hormone levels may exacerbate or interfere with treatment for people who have existing thyroid conditions such as hypo or hyperthyroidism.

Claim: These interactions could potentially lead to amplified side effects or reduce the intended effectiveness of the medications.
Fact check: True. Herb-drug interactions can lead to amplified side effects or reduced effectiveness of medications.

Interactions between herbs and medications may affect how a medication works in the body, causing unwanted side effects or lessening a drugs efficacy.

Claim: Pregnant and breastfeeding women should use caution with lemon balm.
Fact check: True. Use of lemon balm during pregnancy and breastfeeding requires caution.

Due to limited safety research, pregnant or breastfeeding women should consult their doctors before taking lemon balm.

Claim: There isn’t enough reliable research to confirm its safety during pregnancy or breastfeeding.
Fact check: True. The safety of lemon balm during pregnancy and breastfeeding is not fully established due to lack of research.

Current research data is not sufficient to establish the safety of lemon balm during pregnancy or breastfeeding, further study is needed to clarify.

Claim: It’s crucial to inform your doctor about any herbal supplements you are taking.
Fact check: True. It is important to inform your doctor about the use of any herbal supplements.

In order to prevent potential drug interactions and ensure the safety and effectiveness of medical care, it is important to inform your doctor of herbal supplements used.

Claim: The appropriate dose depends on several factors.
Fact check: True. The correct dose of lemon balm varies based on different factors.

Dosage is dependent on factors such as the condition being treated, the form of lemon balm used and an individuals specific health profile.

Claim: Keep in mind that taking more is not always better.
Fact check: True. High doses of lemon balm may increase the risk of side effects.

Taking more than the recommended dose of lemon balm may increase unwanted effects.

Claim: Higher doses of lemon balm can increase your risk of side effects.
Fact check: True. Higher doses of lemon balm may lead to increased side effects.

The risk of experiencing side effects tends to increase with higher doses of lemon balm.

Claim: Lemon balm may interact with various types of medications.
Fact check: True. Lemon balm may have interactions with certain medications.

It is important to be aware of potential interactions between lemon balm and other drugs taken concurrently, since it may change their intended effect.

Claim: Lemon balm may also interact with thyroid medications.
Fact check: Potentially True. Lemon balm may interact with thyroid medications.

Since lemon balm can affect thyroid hormone levels it may interfere with the effectiveness of thyroid medications.

Claim: The herb may interfere with the body’s use of thyroid hormones.
Fact check: Potentially True. Lemon balm may interfere with the body’s use of thyroid hormones.

Lemon balm may affect the metabolism or action of thyroid hormones, which could affect the effectiveness of thyroid medications or exacerbate existing thyroid conditions.

Claim: People with thyroid disorders should be especially careful when considering lemon balm.
Fact check: True. People with thyroid disorders should exercise caution when using lemon balm.

Those with thyroid conditions need to be aware of the potential impact of lemon balm on hormone levels, since it may interfere with treatments or worsen their condition.

Claim: Individuals scheduled for surgery should discontinue lemon balm use.
Fact check: True. Discontinuation of lemon balm is recommended prior to surgery.

It is recommended that lemon balm is stopped prior to surgery due to its sedative properties, which may interact with anesthesia.

Claim: The herb can potentially enhance the effects of anesthesia.
Fact check: Potentially True. Lemon balm may interact with anesthesia.

Lemon balm’s sedative properties may have an additive effect when combined with anesthesia, potentially leading to increased sedation or other complications.

Claim: The dietary supplement industry has less stringent oversight, which can lead to variability in product quality.
Fact check: True. There is less stringent oversight of dietary supplements than other industries.

The dietary supplement industry generally has less regulatory oversight than that of drugs, leading to inconsistencies in product quality, purity, and potency.

Claim: The Food and Drug Administration (FDA) does not approve herbal supplements before they go on sale.
Fact check: True. The FDA does not approve dietary supplements before they are marketed.

The FDA does not require pre-market approval for herbal supplements unlike prescription and over the counter drugs. They take action after a product is on the market, if problems are found.

Claim: The safety and effectiveness of long-term lemon balm use are not fully understood.
Fact check: True. Long-term safety and efficacy data is lacking.

Most studies of lemon balm are short term, more long term research is needed to understand long term risks or benefits of continuous use.

Claim: Tolerance may develop with regular daily use over long periods.
Fact check: Potentially True. There is some concern that tolerance may develop with consistent lemon balm use.

There is a possibility that tolerance might develop with long-term use, meaning more may be needed to achieve the same effect. However, further research is needed to fully confirm this.

Claim: Long-term safety data is currently lacking.
Fact check: True. Research on long-term safety is limited.

Most studies on lemon balm evaluate the short term use, data on long term safety is not robust.

Claim: Some experts advise cycling lemon balm use.
Fact check: True. Some experts suggest cycling use of lemon balm.

The use of periodic breaks, such as taking breaks from regular use may help to mitigate the risk of tolerance and other long-term use concerns.

Claim: Remember that ‘natural’ does not automatically mean safe for long-term use.
Fact check: True. Natural products are not inherently safe for long-term use.

It is important to be aware that some natural products may be unsafe with long term use and that ‘natural’ is not synonymous with ‘safe’.

Claim: Chamomile tends to be gentler and less likely to cause drowsiness, while lemon balm may be more effective for managing anxiety.
Fact check: Potentially True. Chamomile is considered gentler, while lemon balm may be more effective for anxiety.

Lemon balm has been shown in some studies to have anxiolytic effects, while chamomile is considered to be a more gentle sedative.

Source: “The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis” https://pubmed.ncbi.nlm.nih.gov/34449930/

Claim: Valerian may cause more side effects, including vivid dreams.
Fact check: True. Valerian has some side effects that are not common with lemon balm.

Valerian is more likely to cause side effects such as vivid dreams, grogginess or stomach upset compared to lemon balm.

Claim: Some herbs may interact or have additive effects, which may not be desirable.
Fact check: True. Combining herbs can lead to interactions or additive effects.

There is a risk of potential herb-herb interactions that can lead to synergistic or additive effects which may increase side effects.

Claim: There’s no evidence that lemon balm causes liver damage in normal doses.
Fact check: True. There is no evidence lemon balm causes liver damage at normal doses.

Studies to date have not shown liver damage with lemon balm use in normal doses, but more research may be needed.

Claim: However, very high doses might stress the liver.
Fact check: Potentially True. Very high doses of lemon balm may stress the liver.

Although rare, excessive amounts of lemon balm may increase stress on the liver, this is more concerning for people with underlying liver conditions.

Claim: Short-term daily use appears safe for most people.
Fact check: True. Short term daily use is generally considered safe for most individuals.

Studies have indicated short-term usage of lemon balm to be well tolerated by the majority of people.

Claim: Long-term daily use lacks research.
Fact check: True. There is not enough data to determine the safety of long-term use.

Most studies on lemon balm are short term and more long term research is needed to determine long term effects.

Claim: Lemon balm may interact with some antidepressants, especially SSRIs.
Fact check: Potentially True. Lemon balm may interact with certain antidepressants, especially SSRIs.

There is a potential for interactions with certain antidepressant medications, especially SSRIs, with increased drowsiness as a possible side effect.

Claim: It could increase drowsiness or affect how the body processes the medication.
Fact check: True. Lemon balm may increase drowsiness or interfere with how medications are processed.

Lemon balm may have additive sedative effects when taken with antidepressants, potentially causing increased drowsiness. It may also alter the metabolism of some drugs.

Claim: While rare, some people report increased anxiety with lemon balm.
Fact check: Potentially True. There are reports of increased anxiety with lemon balm in some individuals.

Although uncommon, some individuals may experience an increase in anxiety symptoms when taking lemon balm, due to individual sensitivity.

Claim: If anxiety worsens, stop use and consult a healthcare provider.
Fact check: True. It is recommended to discontinue use and consult a doctor if anxiety worsens.

If you notice an increase in your anxiety symptoms with lemon balm, it is important to stop use and consult a healthcare professional for guidance.

Claim: For anxiety or stress relief, some people feel results within 30 minutes.
Fact check: Potentially True. Onset of effects can vary, but some individuals report symptom relief within 30 minutes.

Many individuals report noticeable effects within 30 minutes for anxiety or stress management but this can vary.

Claim: For sleep benefits, it may take a few hours.
Fact check: Potentially True. It may take a few hours for sleep benefits to be noticed.

It may take a few hours for the sleep related benefits of lemon balm to be noticed. It is often recommended to be taken 1-2 hours before bed.

Claim: Consistent use over several weeks may be needed for full effects.
Fact check: Potentially True. Consistent use over a few weeks may be needed for the full benefits of lemon balm.

Some effects of lemon balm may require consistent use over several weeks for full efficacy. However results vary.

Claim: Lemon balm is not considered addictive.
Fact check: True. Lemon balm is not known to be addictive.

Lemon balm is not thought to be physically addictive, although psychological dependence is possible.

Claim: However, people may become psychologically dependent on its calming effects.
Fact check: True. Psychological dependence is possible with consistent lemon balm use.

Some people may develop a psychological dependence on its calming effects if they rely on it heavily.


Medically reviewed and fact checked

Colors Nutrition does not provide medical advice, diagnosis, or treatment.