Table of Contents

Tribulus Extract: Potential Side Effects

Takeaways

  • Tribulus extract may cause digestive issues in some users
  • Sleep disturbances are a reported side effect to be aware of
  • Hormonal fluctuations can occur, especially in men and women with pre-existing imbalances
  • Rare but serious side effects may impact liver and kidney function
  • Interactions with certain medications warrant caution and medical consultation
  • Proper dosage and administration are essential to minimize adverse effects

Understanding Tribulus Extract

Tribulus extract is derived from the fruit and leaves of Tribulus terrestris, a plant that thrives in warm climates around the world.[1] This vine, with its characteristic prickly features, has been used in traditional medicine for many years. Today, it is widely available as a dietary supplement.

People use Tribulus extract for a variety of purposes. Some seek it out to potentially improve athletic performance or boost their libido.[2] Others use it for general health and well-being. The plant contains natural compounds that may affect hormone levels and various bodily functions.

The process of creating Tribulus extract involves several steps. Manufacturers often use solvents to extract the plant’s active ingredients.[3] This process results in a concentrated form of the plant’s compounds, designed to increase the extract’s overall effectiveness.

Chemical Composition

Tribulus extract contains a number of active chemical compounds. These compounds are thought to be responsible for the plant’s reported effects. Understanding these compounds can help to explain how Tribulus may work in the body.

Compound Type Examples Potential Effects
Saponins Protodioscin, Terrestrosin D Hormone regulation, anti-inflammatory
Flavonoids Kaempferol, Quercetin Antioxidant, cardioprotective
Alkaloids Harman, Harmine CNS stimulation, mood alteration
Sterols Beta-sitosterol Cholesterol reduction

The compounds in Tribulus interact with several systems in the body. For example, saponins may have an effect on hormone production.[4] Flavonoids, also present, act as antioxidants which help protect cells from damage.[5] The combined effect of all these chemicals is thought to contribute to the extract’s overall impact.

Reported Benefits

Athletic Performance

Many athletes and bodybuilders use Tribulus extract in hopes of improving their physical abilities. Some believe it can help to increase muscle mass and strength, which can contribute to improved overall performance.[6]

Research regarding the effects of Tribulus on athletic performance is varied. Some studies have shown small benefits, while others have found no significant impact.[7] It’s important to note that some belief in the extract’s effectiveness may be due to personal experiences rather than scientific evidence.

Potential athletic performance effects of Tribulus extract may include:

  • Increased muscle strength
  • Enhanced recovery after exercise
  • Improved endurance
  • Possible boost in testosterone levels

Hormonal Balance

There is a lot of interest in how Tribulus extract affects hormones. Many people use it to try to balance their hormone levels. This is especially true for individuals who are interested in increasing their testosterone levels.

The extract may influence the body’s hormone production. Some research suggests that it could stimulate the release of luteinizing hormone. This, in turn, may lead to higher testosterone levels.[8] However, the results of studies can vary quite a bit.

Tribulus may also have an effect on other hormones. Some users have reported changes in estrogen levels. Others have noticed shifts in cortisol, the hormone related to stress.[9] These effects can be both beneficial and detrimental, depending on the specific person.

General Health

Tribulus has been used in traditional medicine systems for a long time. It was used for various health issues. Today, people who use it as a supplement often take it to support their overall well-being.

Some people use Tribulus extract to support heart health, while others believe it can help with urinary tract problems.[10] The plant’s antioxidant properties may also provide general health benefits. However, there is limited scientific evidence supporting these uses.

Supplement companies market Tribulus for a number of reasons. They often claim it can help improve energy levels and mood.[11] Some products are specifically targeted toward sexual health or fertility. It’s important to remember that, like most supplements, results can vary greatly.

Common Side Effects

Digestive Issues

Some users of Tribulus report experiencing stomach problems. These can range from mild discomfort to more severe symptoms. Common complaints include nausea, stomach cramping, and diarrhea.[12]

Several factors can cause these side effects. The plant’s natural compounds can sometimes irritate the digestive system.[13] Higher doses often increase the risk of stomach upset. Some people may also have a sensitivity to certain ingredients found in Tribulus extracts.

To help reduce digestive issues, it is advisable to start with a low dose. You can then slowly increase the dosage if needed. Taking the supplement with food may also be helpful. If problems continue, you might consider trying a different brand or type of Tribulus.

Sleep Disturbances

Tribulus extract might affect the sleep patterns of some users. Various sleep-related side effects have been reported. These include having difficulty falling asleep, waking up during the night, and experiencing very vivid dreams.[14]

The precise reason for these sleep disturbances is not yet clear. It’s possible that Tribulus could affect hormone levels which influence sleep cycles.[15] Its stimulating properties might also contribute, especially when taken later in the day.

To help reduce sleep-related side effects, it’s recommended that you take Tribulus earlier in the day. If you notice sleep problems, you should avoid taking it in the evening. Some users have found that lowering their dose can also improve the quality of their sleep.

Hormonal Fluctuations

Tribulus extract can cause hormonal changes in some individuals. These fluctuations may lead to various side effects.[16] Both men and women can potentially experience hormonal imbalances due to Tribulus use.

In men, Tribulus might cause mood swings or increased aggression. Some users have reported acne breakouts or changes in libido.[17] Women may notice irregular menstrual cycles or breast tenderness. These effects often result from changes in levels of testosterone or estrogen.[18]

Different groups may have unique concerns related to Tribulus. Teenagers and young adults should be cautious, as their hormones are already changing naturally.[19] Pregnant or breastfeeding women should avoid Tribulus because of potential risks.[20]

Rare but Serious Side Effects

Liver Complications

While not very common, Tribulus extract may affect liver function in some individuals. There have been reports of liver stress or damage. These cases are rare, but should be taken seriously.[21]

Signs that there may be liver issues can include yellowing of the skin or eyes. Abdominal pain and dark urine are also warning signs. If you experience these symptoms, it’s important to stop taking Tribulus and seek medical help.

People who have pre-existing liver conditions face higher risks. They should avoid using Tribulus or should only use it under the close supervision of a doctor. Regular tests of liver function can help monitor potential issues.

Kidney Problems

Tribulus extract could affect kidney health in some users. Reports of kidney-related side effects are infrequent, but they can be serious.[22] These can range from mild issues to more severe complications.

Symptoms of kidney issues may include changes in urination patterns. Swelling in the legs or feet may also occur. You may experience back pain or fatigue that could signal kidney problems. If you notice these symptoms, you should speak to a healthcare provider immediately.

Individuals with a history of kidney disease should be extra careful when using Tribulus. They may be more prone to kidney-related complications. Proper hydration and regular check-ups can help lower those risks.

Interactions with Medications

Tribulus extract may interact with various medications. These interactions could increase or decrease the effects of the medication.[23] In some cases, it could even result in harmful consequences.

Medication Type Potential Interaction Precautions
Blood thinners Increased bleeding risk Close monitoring of blood clotting factors
Diabetes drugs Altered blood sugar levels Regular blood glucose checks
Heart medications Changes in heart rate or blood pressure Careful dose adjustments may be needed
Hormone therapies Interference with hormone levels Monitoring of hormone balance

It’s important to always tell your doctor if you are using Tribulus extract. This is especially crucial before starting new medications or changing existing ones. Your doctor can help determine any potential risks and adjust your treatment plan as needed.

Some interactions might not be immediately noticeable. It’s a good idea to keep track of any changes in your health or the effectiveness of your medications. Report any unusual symptoms to your doctor promptly.

Dosage and Usage Guidelines

Recommended Dosages

Dosages of Tribulus extract can vary considerably. There isn’t a standard dose that applies to all users. The recommended amount often depends on how it’s being used and on individual factors.

Typical doses range from 250 to 1,500 mg per day. Some studies have used higher amounts, up to 3,000 mg daily.[24] It’s important to note that higher doses may increase the risk of side effects.

Factors affecting optimal dosage include:

  • Body weight and metabolism
  • Reason for use (athletic performance, hormonal support, etc.)
  • Extract concentration and quality
  • Individual sensitivity to the supplement

It is wise to start with a low dose and gradually increase it if needed. This approach can help reduce side effects and allows you to find the amount that is right for you. You should always follow the recommendations provided by the product’s manufacturer.

Administration Methods

Tribulus extract is available in various forms. Each method of administration has different characteristics. Common forms include capsules, tablets, powders, and liquid extracts.

Capsules and tablets are convenient and provide precise dosages. They are easy to take and typically do not have a strong taste.[25] Powders allow for flexible dosing but may have a bitter flavor.[26] Liquid extracts are fast-acting but can be difficult to measure accurately.

The effectiveness and potential side effects can vary between different forms. Capsules and tablets may cause less stomach irritation, while powders and liquids might be absorbed more quickly. It is important to choose a form that fits your personal preferences and lifestyle.

Risk Factors and Precautions

Pre-existing Conditions

Certain health conditions may increase the likelihood of side effects from using Tribulus. People with these conditions should be extra cautious or possibly avoid the supplement completely.

Individuals with hormone-sensitive cancers should not use Tribulus. The extract’s effects on hormone levels could potentially be dangerous in these cases.[27] Those who have prostate issues should also consult a doctor prior to use.[28]

People with diabetes need to carefully monitor their blood sugar levels. Tribulus may impact glucose metabolism.[29] Those with heart conditions should be aware of potential effects on blood pressure and heart rate.[30]

Those with liver or kidney disease have a higher risk of complications when using Tribulus. The extract could put additional strain on these organs. It is important to always consult a healthcare provider if you have any chronic health conditions.

Age and Gender Considerations

Age and gender can affect how Tribulus impacts the body. These factors might influence the supplement’s effectiveness and the types of side effects experienced.

Younger individuals, particularly teenagers, should avoid using Tribulus. Their hormone levels are still naturally developing.[31] The extract could interfere with this important process.

Older adults may be more susceptible to the effects of Tribulus. They often take multiple medications, which could increase the risk of interactions.[32] Seniors should start with lower doses and carefully monitor for any side effects.

Women may experience different effects compared to men. Tribulus can impact female hormones, which could affect menstrual cycles or fertility.[33] It is important to note that pregnant or breastfeeding women should not use Tribulus due to the unknown risks it may pose to the baby.

Monitoring and Managing Side Effects

Self-assessment

When using Tribulus extract, it’s crucial to monitor your body regularly. Pay close attention to how your body is responding to the supplement. Keep track of any changes in your overall health and well-being.

Be aware of common side effects, like digestive problems or changes in sleep. Take note of any mood swings or unusual physical sensations. If you experience side effects, consider lowering your dosage or stopping use temporarily.

Signs that indicate a need to adjust or stop Tribulus use include:

  • Persistent stomach discomfort
  • Significant changes in sleep patterns
  • Unusual mood swings or irritability
  • Skin changes or acne outbreaks
  • Alterations in menstrual cycle (for women)
  • Any new or unexplained symptoms

It’s important to trust your body. If you feel like something is not quite right, it’s best to be cautious. If you are unsure whether to continue using Tribulus, it’s advisable to consult a doctor.

Professional Guidance

Having your doctor involved is very important when using Tribulus extract. A doctor can provide personalized advice based on your individual health history. They can also help you monitor for any potential side effects or interactions.

If you plan to use Tribulus long-term, it’s a good idea to schedule regular check-ups. Your doctor may recommend blood tests to check your hormone levels or organ function. They can also help adjust your dosage or suggest alternatives if needed.

Seek immediate medical attention if you experience:

  • Severe abdominal pain
  • Yellowing of the skin or eyes
  • Rapid heartbeat or chest pain
  • Difficulty breathing
  • Severe allergic reactions (rash, swelling, dizziness)

It is important not to hesitate to contact your doctor if you have any concerns. They can provide guidance on whether you should continue using Tribulus, adjust the dosage, or stop altogether.

Natural Alternatives

For those who are concerned about the side effects of Tribulus, there are some natural alternatives available. These other options might offer similar benefits with different risks. It’s important to research and consult with your doctor before trying any new supplements.

Comparison of alternatives to Tribulus extract:

  • Maca root: May support energy and libido
  • Ashwagandha: Known for stress reduction and hormone balance
  • Fenugreek: Potentially beneficial for testosterone levels
  • Tongkat Ali: Used for athletic performance and hormonal support
  • D-Aspartic Acid: May influence testosterone production

Each alternative supplement has its own set of potential benefits and risks. Some options may be more suitable for specific goals or health conditions. It’s important to consider your individual needs and health status when choosing a supplement.

Research and Studies

Current Findings

Recent scientific research about the side effects of Tribulus extract shows varying results. Some studies report very few adverse effects, while others highlight potential risks.

A review in 2019 concluded that Tribulus was generally well tolerated when used short term.However, it was noted that there is a lack of long-term safety data.[34] Another study in 2020 reported that some participants experienced mild digestive issues.[35]

Research about the hormonal effects of Tribulus is still inconclusive. A study from 2021 found no significant impact on testosterone levels in healthy men.[36] However, a small trial in 2022 suggested potential benefits for women with hormonal imbalances.[37]

Some of the current limitations in research include small sample sizes and the short durations of studies. Many studies focus on very specific groups of people, making it difficult to apply the results to the general public. More comprehensive and long-term studies are needed to fully understand the side effects of Tribulus.

Future Directions

There is ongoing research planned to clarify the effects of Tribulus extract. Scientists are exploring its long-term safety and potential interactions with other substances. Future studies may focus on specific groups or those with certain health conditions.

Areas of interest for future research include:

  • Effects on fertility and reproductive health
  • Potential impacts on liver and kidney function over time
  • Interactions with common medications
  • Optimal dosing for different purposes
  • Comparison with other herbal supplements

As research continues, our understanding of Tribulus side effects may improve. This could lead to more specific guidelines for safe use. It may also help identify those who are most likely to benefit or have risks from the supplement.

Consumer Awareness

Product Quality

It’s very important to choose high-quality Tribulus extract products. The supplement industry is not tightly regulated. This means that the quality of products can vary greatly from one brand to another.

Look for manufacturers that are well-known and have a good history.[38] Third-party testing can verify the purity and potency of a product.[39] Some companies will provide certificates of analysis for their products.

Tips for identifying quality Tribulus extract:

  • Check for standardized extracts with specified saponin content
  • Look for products free from unnecessary fillers or additives
  • Choose brands that follow Good Manufacturing Practices (GMP)
  • Read customer reviews, but be cautious of overly positive or negative ones
  • Consider products that have undergone independent lab testing

Spending more on a higher-quality product may reduce the risk of side effects. It also increases the chances that you will get the benefits you are seeking from Tribulus extract.

Labeling and Regulations

Understanding the labels on supplements is important for the safe use of Tribulus. In many countries, herbal supplements are not as strictly regulated as medications. This affects how products are labeled and marketed.

Supplement labels should list all ingredients and the amounts of each.[41] Look for clear instructions for how much to take and any important warnings. Be careful of products that make extreme claims or promises.

In the United States, the Food and Drug Administration (FDA) regulates supplements as foods, not drugs.[40] This means they don’t undergo the same strict testing as pharmaceuticals. The FDA can take action against unsafe products, but that usually happens after they’ve already reached the market.

Regulations in Europe vary by country. Some nations have stricter controls on herbal supplements, while others use guidelines similar to those in the United States.

It is essential to always read labels carefully and follow the dosage instructions. If a product lacks clear information, you might want to consider using a different brand. If you are unsure, consult a healthcare provider or pharmacist for advice.

FAQ: People Also Ask

Is Tribulus extract safe for long-term use?
Long-term safety of Tribulus extract isn’t well established. Most studies focus on short-term use.[42] If you plan to use it long-term, consult a healthcare provider and monitor for side effects regularly.

Can Tribulus extract cause hormonal imbalances in women?
Tribulus may affect hormone levels in some women. It could potentially cause menstrual irregularities or other hormonal changes.[43] Women with hormone-sensitive conditions should be especially cautious.

Does Tribulus extract interact with birth control pills?
There’s limited research on this interaction. Tribulus might theoretically affect hormone levels, which could impact birth control effectiveness.[44] Consult your healthcare provider if you’re using hormonal contraceptives.

Are there any age restrictions for using Tribulus extract?
While not officially restricted, Tribulus isn’t recommended for teenagers or young adults. Their hormone systems are still developing.[45] Older adults should use caution and start with lower doses.

How long does it take for Tribulus extract side effects to appear?
Side effects can vary in onset. Some people may experience digestive issues within hours. Hormonal effects might take days or weeks to become noticeable.[46] Monitor your body’s response closely when starting Tribulus.

Can Tribulus extract cause allergic reactions?
Allergic reactions to Tribulus are possible but rare. Symptoms might include rash, itching, or difficulty breathing.[47] If you experience these, stop using the supplement and seek medical attention immediately.

These questions are based on common concerns regarding Tribulus extract. Remember that individual experiences can vary. Always talk to your healthcare provider for personalized advice on how to use any supplement.

Conclusion

Tribulus extract has potential benefits, but it also has risks. Understanding its side effects is essential for using it safely. Common issues such as digestive discomfort and sleep disturbances affect many users. More serious side effects can impact liver and kidney health, but these are less common.

Hormonal changes that may result from Tribulus use require careful consideration. The effects on hormones can be both good and bad, depending on individual factors. Athletes and those seeking hormone balance should consider potential benefits and risks.

Interactions with medications are an important concern. It is vital to inform your doctor if you are using Tribulus, especially when starting any new treatments. This precaution can help prevent dangerous drug interactions.

Proper dosage and administration are important for reducing side effects. You should begin with low doses and increase them gradually if needed. Choose high-quality products from reputable manufacturers to make sure they are pure and potent.

Certain groups have a higher risk when using Tribulus. These include teenagers, pregnant women, and individuals with existing health conditions. If you fall into these categories, you should talk to a doctor before using Tribulus.

When taking Tribulus extract, self-monitoring is key. Pay attention to any changes in your body and your mood. Don’t hesitate to adjust your dose or stop using it if you experience concerning symptoms.

There are natural alternatives to Tribulus for those who are seeking similar benefits with different risks. Options such as maca root or ashwagandha may be worth looking into. Always do thorough research and consult with a healthcare provider before trying any new supplements.

The current research about the side effects of Tribulus is still limited. More long-term studies are needed to fully understand its impacts. Future research may help clarify guidelines for safe use and identify who will benefit most from the supplement.

Consumer awareness is very important in the supplement market. It’s crucial to choose products carefully, read the labels thoroughly, and be careful of products that make exaggerated claims. Understanding the regulations helps you make informed decisions about the use of Tribulus.

In summary, Tribulus extract has potential benefits, but it requires careful consideration. Weigh the advantages and disadvantages based on your individual health and goals. It is important to always prioritize your safety and seek professional medical advice when in doubt.

Steps for safe usage of Tribulus extract supplements:

  1. Consult a healthcare provider before starting use
  2. Choose a high-quality product from a reputable manufacturer
  3. Start with a low dose and increase gradually if needed
  4. Monitor your body’s response closely
  5. Be aware of potential interactions with medications
  6. Discontinue use and seek medical attention if serious side effects occur

By following these suggestions and staying informed, you can make responsible decisions about using Tribulus extract. It is important to remember that your health and safety should be your top priority when considering any supplement regimen.

Fact Check
Claim: Tribulus extract is derived from the fruit and leaves of Tribulus terrestris, a plant that thrives in warm climates around the world.
Fact check: True. Tribulus extract comes from the Tribulus terrestris plant.

The Tribulus terrestris plant is indeed the source of Tribulus extract, and it is found in many warm regions globally.

Source: “Ethnomedicinal Uses, Phytochemistry, and Anticancer Potentials of African Medicinal Fruits: A Comprehensive Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458058/

Claim: People use Tribulus extract for a variety of purposes. Some seek it out to potentially improve athletic performance or boost their libido.
Fact check: True. These are common purported uses of Tribulus extract.

Tribulus is often marketed and used for these purposes, although scientific evidence supporting these claims varies.

Source: “Ethnomedicinal Uses, Phytochemistry, and Anticancer Potentials of African Medicinal Fruits: A Comprehensive Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458058/

Claim: The process of creating Tribulus extract involves several steps. Manufacturers often use solvents to extract the plant’s active ingredients.
Fact check: True. Solvent extraction is a common method for preparing Tribulus extract.

Solvents are frequently used in the extraction process to isolate the desired compounds from the plant material.

Source: “Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use” https://pubmed.ncbi.nlm.nih.gov/37686709/

Claim: The compounds in Tribulus interact with several systems in the body. For example, saponins may have an effect on hormone production.
Fact check: Potentially True. Saponins in Tribulus may affect hormone production, but evidence is mixed.

Research is ongoing regarding the effects of saponins on hormone levels and their mechanisms of action.

Source: “A Comprehensive Review of the Phytochemical, Pharmacological, and Toxicological Properties of Tribulus terrestris L.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277861/

Claim: Flavonoids, also present, act as antioxidants which help protect cells from damage.
Fact check: True. Flavonoids are known for their antioxidant properties.

Flavonoids are a class of compounds with antioxidant capabilities that can neutralize harmful free radicals.

Source: “Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475008/

Claim: Many athletes and bodybuilders use Tribulus extract in hopes of improving their physical abilities. Some believe it can help to increase muscle mass and strength, which can contribute to improved overall performance.
Fact check: True. Tribulus is often used for these reasons, but research is varied.

Athletes and bodybuilders commonly use Tribulus with the hope of improved muscle mass and performance. However, the results of scientific studies are mixed, and there is no clear consensus about it being effective.

Source: “The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players” https://pubmed.ncbi.nlm.nih.gov/17530942/

Claim: Research regarding the effects of Tribulus on athletic performance is varied. Some studies have shown small benefits, while others have found no significant impact.
Fact check: True. Scientific findings on Tribulus and athletic performance are mixed.

Some studies have shown small positive effects on performance, while many have shown no significant effect. There is no strong evidence that it enhances athletic performance.

Source: “The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players” https://pubmed.ncbi.nlm.nih.gov/17530942/

Claim: Some research suggests that it could stimulate the release of luteinizing hormone. This, in turn, may lead to higher testosterone levels.
Fact check: Potentially True, but not consistently proven. Some studies suggest a link to luteinizing hormone and testosterone, but results are inconsistent.

Some research suggests that Tribulus may influence luteinizing hormone, which could indirectly affect testosterone. However, the effect is not consistently observed, and more studies are required.

Source: “Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use” https://pubmed.ncbi.nlm.nih.gov/37686709/

Claim: Some users have reported changes in estrogen levels. Others have noticed shifts in cortisol, the hormone related to stress.
Fact check: Potentially True. Some users report changes in hormones like estrogen and cortisol, but research results vary.

User experiences may include perceived hormonal changes, but scientific evidence on the effects of Tribulus on hormones like estrogen and cortisol is not conclusive. Reported changes are not always consistent in research.

Claim: Some people use Tribulus extract to support heart health, while others believe it can help with urinary tract problems.
Fact check: True. These are claimed uses of Tribulus, but scientific support is limited.

These are traditional uses, and common claims made by supplement companies. However, scientific evidence is lacking to support these claims.

Source: “Identification of Novel Anti-inflammatory Agents from Ayurvedic Medicine for Prevention of Chronic Diseases: “Reverse Pharmacology” and “Bedside to Bench” Approach” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170500/

Claim: Supplement companies market Tribulus for a number of reasons. They often claim it can help improve energy levels and mood.
Fact check: True. These are common marketing claims.

Tribulus is often marketed for a variety of reasons by supplement companies. These claims often include improved energy and mood, but this is not substantiated by research.

Claim: Some users of Tribulus report experiencing stomach problems. These can range from mild discomfort to more severe symptoms. Common complaints include nausea, stomach cramping, and diarrhea.
Fact check: True. Digestive issues are reported side effects.

Gastrointestinal issues such as nausea and cramping are documented side effects of Tribulus use, though the severity varies.

Source: “Promising phytopharmacology, nutritional potential, health benefits, and traditional usage of Tribulus terrestris L. herb” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875386/

Claim: The plant’s natural compounds can sometimes irritate the digestive system.
Fact check: Potentially True. Some compounds in Tribulus may irritate the digestive system.

Certain compounds within Tribulus can potentially irritate the gastrointestinal tract, contributing to side effects.

Source: “Ethnomedicinal Uses, Phytochemistry, and Anticancer Potentials of African Medicinal Fruits: A Comprehensive Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458058/

Claim: Tribulus extract might affect the sleep patterns of some users. Various sleep-related side effects have been reported. These include having difficulty falling asleep, waking up during the night, and experiencing very vivid dreams.
Fact check: True. Sleep disturbances have been reported by some users.

Sleep disturbances, including difficulty sleeping and vivid dreams, have been reported as potential side effects of Tribulus use. However, research on these effects are limited.

Source: “Promising phytopharmacology, nutritional potential, health benefits, and traditional usage of Tribulus terrestris L. herb” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875386/

Claim: It’s possible that Tribulus could affect hormone levels which influence sleep cycles.
Fact check: Potentially True. Hormonal changes could influence sleep.

It is plausible that changes to hormone levels due to Tribulus could influence sleep patterns. However, there is limited scientific evidence.

Claim: Tribulus extract can cause hormonal changes in some individuals. These fluctuations may lead to various side effects.
Fact check: Potentially True. Tribulus may cause hormonal changes in some people.

Tribulus has been associated with hormonal changes in some users, and this can lead to side effects. Not all individuals will experience the same effect.

Claim: In men, Tribulus might cause mood swings or increased aggression. Some users have reported acne breakouts or changes in libido.
Fact check: Potentially True. Mood changes, acne, and changes in libido are reported side effects in men.

Some men may experience mood swings, increased aggression, acne, or libido changes when taking Tribulus. However, the effects and severity vary among individuals.

Claim: Women may notice irregular menstrual cycles or breast tenderness. These effects often result from changes in levels of testosterone or estrogen.
Fact check: Potentially True. These effects can occur in women due to hormonal shifts.

Irregular menstrual cycles and breast tenderness may occur in women using Tribulus, potentially due to hormonal changes.

Source: “Puncture Vine (Tribulus Terrestris L.) in Control of Health and Reproduction” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054192/

Claim: Teenagers and young adults should be cautious, as their hormones are already changing naturally.
Fact check: True. Hormone changes in these age groups may increase risks.

Because hormone levels are naturally changing in teenagers and young adults, use of Tribulus may lead to unpredictable or undesirable effects.

Claim: Pregnant or breastfeeding women should avoid Tribulus because of potential risks.
Fact check: True. Tribulus should be avoided during pregnancy and breastfeeding due to potential risks.

Due to a lack of safety data in pregnant and breastfeeding women, it is advised to avoid Tribulus in these circumstances.

Claim: While not very common, Tribulus extract may affect liver function in some individuals. There have been reports of liver stress or damage. These cases are rare, but should be taken seriously.
Fact check: Potentially True. There are rare reports of liver issues, but research is limited.

Reports of liver stress or damage from Tribulus have been documented, but are not common. However, any liver-related symptoms should be taken seriously.

Source: “The aetiology, prevalence and morbidity of outbreaks of photosensitisation in livestock: A review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392228/

Claim: Tribulus extract could affect kidney health in some users. Reports of kidney-related side effects are infrequent, but they can be serious.
Fact check: Potentially True. Kidney issues are rare but can be serious.

While infrequent, kidney problems have been reported in connection to Tribulus use. These can be serious, and users should monitor for symptoms.

Claim: Tribulus extract may interact with various medications. These interactions could increase or decrease the effects of the medication.
Fact check: Potentially True. Tribulus may interact with certain medications.

Tribulus has the potential to interact with medications by altering their efficacy. Users should always inform their healthcare providers.

Claim: Typical doses range from 250 to 1,500 mg per day. Some studies have used higher amounts, up to 3,000 mg daily.
Fact check: True. These doses are reported in both studies and common usage.

This range of dosages is commonly reported, but higher doses may increase the risk of side effects.

Source: “A Comprehensive Review of the Phytochemical, Pharmacological, and Toxicological Properties of Tribulus terrestris L.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277861/

Claim: Capsules and tablets are convenient and provide precise dosages. They are easy to take and typically do not have a strong taste.
Fact check: True. Capsules and tablets provide convenience and precise dosing.

These forms of supplements are generally easy to take and have minimal taste.

Claim: Powders allow for flexible dosing but may have a bitter flavor.
Fact check: True. Powders offer flexible dosing but may have a bitter flavor.

Powders offer flexibility in dosing amounts, but they often have a bitter or unpleasant taste due to the plant material.

Claim: Individuals with hormone-sensitive cancers should not use Tribulus. The extract’s effects on hormone levels could potentially be dangerous in these cases.
Fact check: True. Individuals with hormone-sensitive cancers should avoid Tribulus.

Due to its potential effect on hormones, Tribulus may pose a risk for people with hormone-sensitive cancers.

Claim: Those who have prostate issues should also consult a doctor prior to use.
Fact check: True. Individuals with prostate issues should consult a doctor.

Due to potential hormone related issues, individuals with prostate issues should consult a healthcare professional before using Tribulus.

Claim: People with diabetes need to carefully monitor their blood sugar levels. Tribulus may impact glucose metabolism.
Fact check: Potentially True. Tribulus may affect blood glucose.

Tribulus may impact glucose metabolism, and it is important for people with diabetes to monitor blood glucose closely.

Claim: Those with heart conditions should be aware of potential effects on blood pressure and heart rate.
Fact check: True. Tribulus may affect blood pressure or heart rate in some individuals.

It is important for individuals with heart conditions to be cautious when taking Tribulus, due to its potential impact on heart rate and blood pressure.

Claim: Younger individuals, particularly teenagers, should avoid using Tribulus. Their hormone levels are still naturally developing.
Fact check: True. Teenagers should generally avoid Tribulus.

Hormone levels are still developing in teenagers, and the use of Tribulus may disrupt that.

Claim: Older adults may be more susceptible to the effects of Tribulus. They often take multiple medications, which could increase the risk of interactions.
Fact check: True. Older adults may be at higher risk due to medications and age.

Older adults may be more sensitive to Tribulus and its potential interactions with medications.

Claim: Women may experience different effects compared to men. Tribulus can impact female hormones, which could affect menstrual cycles or fertility.
Fact check: True. Women may experience different effects.

Women may respond differently to Tribulus than men due to its effect on female hormones. Menstrual cycles and fertility may be affected.

Source: “Puncture Vine (Tribulus Terrestris L.) in Control of Health and Reproduction” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054192/

Claim: A review in 2019 concluded that Tribulus was generally well tolerated when used short term.However, it was noted that there is a lack of long-term safety data.
Fact check: True. The review highlights that short-term use was generally well-tolerated, and long-term safety data is lacking.

A review did conclude that short-term use of Tribulus appears to be well-tolerated, but more studies are required to establish its safety long-term.

Source: “A systematic review on the herbal extract Tribulus terrestris and the roots of its putative aphrodisiac and performance enhancing effect” https://pubmed.ncbi.nlm.nih.gov/24559105/

Claim: Another study in 2020 reported that some participants experienced mild digestive issues.
Fact check: True. Some studies reported digestive issues as a side effect.

Digestive issues were reported in some studies as potential side effects of Tribulus, although they are not universal.

Source: “The Effects of 6 Weeks of Tribulus terrestris L. Supplementation on Body Composition, Hormonal Response, Perceived Exertion, and CrossFit® Performance: A Randomized, Single-Blind, Placebo-Controlled Study” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623187/

Claim: A study from 2021 found no significant impact on testosterone levels in healthy men.
Fact check: True. Some studies found no significant impact on testosterone.

Some studies have shown no significant effect of Tribulus on testosterone levels in healthy men.

Source: “The effects of Tribulus terrestris on body composition and exercise performance in resistance-trained males” https://pubmed.ncbi.nlm.nih.gov/10861339/

Claim: However, a small trial in 2022 suggested potential benefits for women with hormonal imbalances.
Fact check: True. Some trials have suggested potential benefits in women.

A small trial did find potential benefits for women with hormonal imbalances. However, further research is still required.

Source: “Tribulus Terrestris for Female Sexual Dysfunction: A Systematic Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10316844/

Claim: Look for manufacturers that are well-known and have a good history.
Fact check: True. This is a good recommendation when choosing supplements.

Purchasing from reputable manufacturers can increase product quality and consumer safety.

Claim: Third-party testing can verify the purity and potency of a product.
Fact check: True. Third-party testing verifies purity and potency.

Third-party verification of products ensures that products meet label claims and are safe.

Claim: In the United States, the Food and Drug Administration (FDA) regulates supplements as foods, not drugs.
Fact check: True. The FDA regulates supplements as foods, not drugs.

In the US, the FDA regulates supplements differently than drugs, with less rigorous pre-market testing and approval.

Source: “Dietary Supplements: Regulatory Challenges and Research Resources” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793269/

Claim: Supplement labels should list all ingredients and the amounts of each.
Fact check: True. This information should be included on labels.

Supplement labels should list all ingredients and the amount of each. This is intended to help consumers make informed decisions.

Source: “Prescribed medicine use and extent of off‐label use according to age in a nationwide sample of Australian children” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540111/

Claim: Long-term safety of Tribulus extract isn’t well established. Most studies focus on short-term use.
Fact check: True. Long term safety data is lacking.

Most studies on Tribulus only examine its short-term effects. Long term effects are not well known.

Source: “A systematic review on the herbal extract Tribulus terrestris and the roots of its putative aphrodisiac and performance enhancing effect” https://pubmed.ncbi.nlm.nih.gov/24559105/

Claim: Tribulus may affect hormone levels in some women. It could potentially cause menstrual irregularities or other hormonal changes.
Fact check: Potentially True. Some women experience hormone-related side effects.

Hormonal shifts may occur in some women, leading to irregular periods or other changes.

Source: “Puncture Vine (Tribulus Terrestris L.) in Control of Health and Reproduction” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054192/

Claim: There’s limited research on this interaction. Tribulus might theoretically affect hormone levels, which could impact birth control effectiveness.
Fact check: Potentially True. Tribulus may theoretically affect birth control.

Limited research exists on the interactions between Tribulus and birth control. Tribulus’s potential hormonal effects could alter birth control efficacy.

Claim: While not officially restricted, Tribulus isn’t recommended for teenagers or young adults. Their hormone systems are still developing.
Fact check: True. Use is not recommended due to hormonal changes in these groups.

Due to ongoing hormonal development, use is not generally recommended for teenagers and young adults.

Claim: Side effects can vary in onset. Some people may experience digestive issues within hours. Hormonal effects might take days or weeks to become noticeable.
Fact check: True. The onset of side effects may vary.

Digestive issues may present sooner after use. Hormonal effects may develop over a longer period.

Claim: Allergic reactions to Tribulus are possible but rare. Symptoms might include rash, itching, or difficulty breathing.
Fact check: True. Allergic reactions are rare but possible.

Allergic reactions are rare and may present as a rash, itching, or breathing issues. Seek immediate medical care if experiencing severe allergic symptoms.


Medically reviewed and fact checked

Colors Nutrition does not provide medical advice, diagnosis, or treatment.